Thanks Tina Agree Adam, this was a wonderful summary. Re: Mantle Cell Lymphoma and ME/CFS. It appears there has been formal work on this for some time. From: http://www.wpinstitute.org/news/news_current.html INIP awardSeptember 8, 2007: NCI CCR (Ruscetti)/NIA (Taub) proposal submitted to the Integrative Neural Immune Program's Intramural Research Award competition, entitled "Role of Chronic Inflammatory Stimulation by Active Herpesvirus Infection in Development of Immune Dysfunction and Mantle Cell Lymphoma in Chronic Fatigue Syndrome Patients", unanimously considered by the ad hoc reviewers and the INIP IRA subcommittee as a project that will yield important new interdisciplinary research findings. The award provides a postdoctoral fellow for 3 years to work on the Project with Dr. Ruscetti and Dr. Taub and WPI. Award date Sept 8, 2007. 3 year postdoc funding. Does that mean that we can expect potentially published results around this Sept, 2010? Was the research 3 years long, or have they completed the research, and the postdoc is now helping them write it up and submit it for publication? Or have they already submitted it, and publication is part of that April Surprise? After all, Doc Peterson did report those prelim results at the CFSAC. Anyone? What exactly causes the cancer? In HIV it appears (some of?) the cancers are caused by the particular breed of opportunistic infections one gets. Is this the same thing with XMRV? Do patients develop cancers dependent on their opportunistic infections? But then remember there is evidence to suggest that XMRV itself is oncogenic (prostate cancer). Is it a synergistic situation? Or do all 3 premises hold with XMRV: XMRV itself causes cancer (eg. prostate)? (Some of?) the opportunistic infections, allowed to persiste because of the underlying XMRV retroviral infection - cause cancer. So if you have active and persistent Herpesvirus infection, whether or not you have XMRV, you might get Mantle Cell Lymphoma? The combination of XMRV and opportunistic infections causes get unique or more powerful cancers? The silver lining in the cancer connection is that it DID get the NIH's National Cancer Institute very interested. Remember Stuart LeGrice's comment cited in the Wall St Journal:“NCI [National Cancer Institute] is responding like it did in the early days of HIV,” says Stuart Le Grice, head of the Center of Excellence in HIV/AIDS and cancer virology at NCI http://online.wsj.com/article/SB125501227713473525.html Remember also that closed-door meeting at the NCI in July 2009 to discuss the public health implications of XMRV. Given that Dr Peterson reported the preliminary lymphoma results at the CFSAC, it is possible that NCI was interested not only in the preliminary Science results on XMRV/CFS, and the prostate cancer link, but also the developing Mantle Cell Lymphoma study results. Either way, it would appear that they are "on it". Another silver lining is that if they do make the link between CFS and lymphomas - entirely consistent with a retroviral pathology - we'll then have the voice of the cancer lobby to support our fight for robust biomedical diagnostics and treatment.