So, I have been on valcyte for not quite 6 months now. Just got back new hhv6 titer. It has dropped to 1:320 -- that is from 1:1280 in January. One doctor is telling me that that is a good result and means the valcyte is working. Another thinks that, after 6 months, I should be testing normal at this point and should consider going back to 900 mg twice a day instead of once. I had basically followed the Montoya protocol of 900 twice a day for 3 weeks then once a day after that. I would appreciate if anyone has experience or knowledge about this kind of situation. I'm not sure what to do. I have been feeling really bad lately -- insomnia (even with meds), muscle pain, fatigue. Don't know if its hhv6 or something else. What do I do if it isn't responding to valcyte? That's pretty much the nuclear option already, right?