James Coyne “lays waste” to PACE trial in Edinburgh
Sasha summarises Professor James Coyne's recent no-holds-barred talk on the PACE trial and points you to the slides, video, audio and transcript.
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New Here, Guidance Needed.. 23andMe CBS, MTRR, MTHFR concerns

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by cobain_justinsane, Mar 14, 2013.

  1. dbkita

    dbkita Senior Member

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    Why the connection? Can anyone explain this to me?
     
  2. thegiantess

    thegiantess

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    So, I went ahead and got the sulfite strips from Yasko, but the ones I received seem different than what people on this forum are talking about. I read people making mention of ranges up to 1600! The strips I have go from 10-400. Are these the same? Am I somehow reading this wrong? Thanks!
     
  3. Symptomatic

    Symptomatic Senior Member

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    You need the sulfate strips, not the sulfite strips.
     
  4. dbkita

    dbkita Senior Member

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    You may want to see the latest analysis I did on the CBS activity question in the "Couple of questions" thread.

    P5p intake could easily I believe make up for any differences in the standard C699T and C1080T SNPs for a person with the wild type (i.e. increasing p5p by a sufficient amount could mimic the 10% or so bump in trans-sulfuration flux for someone with the homozygous C669T four hours after a HUGE influx of methionine).

    While p5p can effect it, the idea of "shooting down" or 10x upregulation is not correct based on my analysis.
     
  5. cobain_justinsane

    cobain_justinsane

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    dbkita:

    I posted in the "couple of questions" thread to try and get a better understanding on a couple of points made in the thread.
    I think it's great that you are looking into the CBS issue because there seems to be a lot of disagreement on the issue.
     

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