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New compounded LDN making me really jittery

Discussion in 'General Treatment' started by minkeygirl, Apr 8, 2014.

  1. minkeygirl

    minkeygirl Is Jim Jones alive and well on PR?

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    When I started on LDN a few months ago I realized I had to take it in the morning because it kept me up all night. When I take it in the morning I feel pretty good.

    I recently got a refill from a different source because the compounding pharmacy my doc uses is outrageously expensive and she was not comfortable RX'ing it out of state so I could get it at Skip's.

    I haven't slept in 3 nights, each night getting worse. I realized it must be the LDN at 3 a.m. this morning when I was still up.

    I took one this at 7:30 a.m. morning so I could pay attention to how I felt and I'm feeling really jittery and not in a good way.

    What could be different in this one that is doing it to me? I know they used the Avicel as the binder. I even changed the capsules to see if that was the problem. That doesn't seem to make a difference.

    What could this be? I'd like some ideas before I contact the pharmacy about this.

    Thanks

    I found out the LDN I can take sources their naltrexone from Medisca. The one I can't take is from PCCA.

    I hate when pharmacists tell you you can't be having a reaction to a medication! I am, so WTF?
    Last edited: Apr 8, 2014
  2. ggingues

    ggingues $10 gift code at iHerb GAS343 of $40

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    Concord, NH
    I wouldn't think they would mix up the short versus long release formula, right?

    GG
  3. OverTheHills

    OverTheHills

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    HI Minkey
    I find the LDN I get compounded locally in NZ gives me low mood as a side effect, and so now I get it made up in the US (by Marcos in miami) and posted which is a pain but is worth it for no mood problems. I have never managed to work out which manufacturer/filler/whatever is the problem.
    Good luck
    OTH
  4. minkeygirl

    minkeygirl Is Jim Jones alive and well on PR?

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    @ggingues You know I don't know because I was still amped at 10 pm. and didn't sleep until 3 a.m.

    I"m going to ask them to have it tested. There is no way that was .5 mgs and if it is sustained release then he screwed up. I only paid $30 so it's not horrible.

    At this point I'm afraid to even try another compounder (I had called Skip's but no one was available). I'll stick with Harbor for now.

    Now I just need some sleep.
  5. ggingues

    ggingues $10 gift code at iHerb GAS343 of $40

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    Concord, NH
    Mine says (short-acting), in parenthesis, after the word Naltrexone. FYI

    I had issues with tolerating LDN when I first started it, so thought might be the issue, but it was just my body adjusting to the medication! And the multitude of lifestyle and medications/supplement changes I made at the time. I was on 1.5mg at first, not sure if that is the dosage I started at or if my doc started me at 4.5 mg right off?

    GG
  6. JT1024

    JT1024 Senior Member

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    If you question the prescription, try going back to the pharmacy that made it.

    They should be able to remake your prescription (verifying that they use the short acting form) without a hassle.

    Hope things work out ok for you.
  7. minkeygirl

    minkeygirl Is Jim Jones alive and well on PR?

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    @ggingues I had been taking it so it wasn't a matter of getting used to it. I went back to the first place I got it and got a really good price on 3 months so for now I'm good. I'm too tired to go look at the bottle right now. I'll see. I did suggest to my contact that maybe he did make the long acting which is nuts.

    @JT1024 They already gave me a credit. I'm questioning the compounder there because he used dyed caps which I think added to the problem. I changed them into some clear ones but I still had a big problem, just not as bad.
  8. Lotus97

    Lotus97 Senior Member

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    @minkeygirl
    Which brand did you say worked better? Medisca or PCCA? I just started Medisca and I wanted to make sure it was a good brand because people have said certain generic brands don't work well.
  9. minkeygirl

    minkeygirl Is Jim Jones alive and well on PR?

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    Left Coast
    @Lotus97, It was the Medisca. I talked to my doc and when I run out of these I'm going to get some 50 mgs and crush them and put them in water and use a syringe to dose.

    Some people have done that here and it'll cost me considerably less. Instead of $90 for 3 months it'll cost me about $10 for 6 months.
    Lotus97 and ggingues like this.

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