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New Australian Research Hints our NK cells cannot kill viral infections

Discussion in 'Latest ME/CFS Research' started by alex3619, Aug 22, 2013.

  1. alex3619

    alex3619 Senior Member

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    Logan, Queensland, Australia
    Thanks go to Tom Kindlon for alerting people to this. This is one of

    Most KIRs or Killer-cell Immunoglobulin-like Receptors have an inhibitory function. They detect that a cell is normal, and then stop the NK cell from killing that cell. Viral infected cells have fewer or altered HLA markers, and so there is no inhibition and the cell can be killed. More KIRs implies that in us our NK cells will more often respond to virally infected cells as though they were normal, and not kill the cell.

    http://en.wikipedia.org/wiki/Killer-cell_immunoglobulin-like_receptor
     
  2. Sushi

    Sushi Moderator and Senior Member Albuquerque

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    alex3619

    This is very interesting and might explain a lot! Thanks.

    Sushi
     
  3. alex3619

    alex3619 Senior Member

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    So, for the bonus prize, why do our NK cells have so much KIRDL1? Questions, questions, always more questions.
     
    Ecoclimber and rosie26 like this.
  4. WillowJ

    WillowJ Senior Member

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    if it did not raise a further question, it would not be a very good paper, right?
     
    SOC, rosie26, alex3619 and 2 others like this.
  5. MeSci

    MeSci ME/CFS since 1995; activity level 6

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    The linked document is a very large file and almost crashed my computer. You may find this one more manageable, and it also has an illustrative Figure.
     
    ahimsa and ukxmrv like this.

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