Sabrina, it never occurred to me that melatonin was making me depressed!!! I just keep thinking, Who wouldn't be depressed with this?! Also, phosphorylated serine caused me insomnia, too! My doctor switched me to phosphotidyl serine and that seemed to stop the new insomnia but not help the old insomnia. Regarding medical cannabis, I am so happy you gave me some advice on this. I smoked when I was a teenager, but I'm a different body now AND my lungs are very sensitive to inhaling things. I very tentatively tried smoking cannabis and nothing happened expect I could feel lung irritation. So I tried a vaporizer. Same thing. Fumey lung irritation, but no other effects. I could try more, but I've been a bit nervous. I could try cooking/eating it, but I've been very nervous. Thank you for mentioning indica. If you have any other advice on that, I would love it. I can't take any pain pills, any NSAIDS and having something calm down my system would be wonderful. Thank you!