IVI, the fact you are using the word 'proof' now in parentheses indicates you understand that use of the word previously was problematic, so I'm pleased about that. Alex appears to have been using the Popperian context of falsifiability and disproving in the way I said, so I stand by that. What I think you have a problem understanding is that many people here are not latching onto the WPI as proven until otherwise disproven. What many people want to see is the science pan out until the WPI's claims are correctly disproven, or until enough evidence accrues to enable a reasonable prediction it is correct, and that XMRV is most likely to cause ME/CFS, in which case the possibility of treatment then becomes available. To take your CBT/GET example. IF there was plausible evidence that CBT/GET helps anybody with ME/CFS, people would be taking up that offer. They could not expect 'proof'. The incoherence and implausibility of the claims, followed by the poor empirical adequacy, that CBT/GET helps people with ME/CFS (actual ME/CFS now- not metaphorical fatigue!) is what makes people not want CBT/GET. Your use of the word proof is not correct because you've been misrepresenting (miscontruing, probably) what many - possibly most- people in this community know about science, the issue of CBT/GET and about the whole saga of XMRV. You think they're all emotionally supporting XMRV- which they are not. This may be because of the way the community is being misrepresented by her majesty ERV and the Bad Science mob. ERV believes its her job to educate the plebs that XMRV has nothing to do with ME/CFS - her attendance on the BS forum shows this- which makes her an idiot and unable to grasp the scientific process. The ME/CFS community is mostly waiting for the science to pan out- free from politics- and for good science to prevail. If they don't like psychogenic explanations, it's because they are implausible- products of badly done 'science'. But none of this can adequately be explained by claiming 'proof' is needed. Most people in this community have become only too aware of the problems of that word when applied to the scientific process.