Isn't Singh working on a spinal fluid study? Wonder how that's going. http://onlinelibrary.wiley.com/doi/... on Saturday, 5th Feb between 10:00-12:00 GMT Only a small abstract: Analysis of cerebrospinal fluid from chronic fatigue patients for multiple human ubiquitous viruses and XMRV Recent reports showed many patients with chronic fatigue syndrome (CFS) harbor a retrovirus, xenotropic murine leukemia-related virus (XMRV) in blood; other studies could not replicate this finding. A useful next step would be to examine cerebrospinal fluid because in some patients CFS is thought to be a brain disorder. Finding a CNS microbe would have greater significance than in blood because of the integrity of the blood-brain-barrier. We examined, but did not find XMRV, nor multiple common other viruses in cerebrospinal fluid from 43 CFS patients using PCR techniques, suggesting exploration of other causes or pathogenetic mechanisms is warranted. Ann Neurol 2011.