I am looking for any suggestions for immune modulators that will balance both TH-1 and TH-2. In addition to CFS, I have an autoimmune condition and post-concussion syndrome (which is caused by a persistent neuroinflammatory cascade in the brain brought on by head trauma). I have elevated IL-12, and INF-gamma. My blood test also shows elevated IL-10, and notes the strong connection between this cytokine and autoimmune activity. I'm looking to tamp down the TH-1 side of the immune system without up-regulating TH-2. The neurologist that I’m working with to treat the PCS says the objective is to stop the inflammatory cascade in the brain so it can heal and we must also tamp down the general autoimmune activity to do this. I tried taking LDN last year (before the head injury) and it crashed my adrenals. I recently tried Moducare (plant sterols) but it seemed to make me feel worse. The doctor had me try pycnogenol to tamp down TH-1, but I felt worse. I am currently taking fish oil, vitamin D and a high potency Xymogen probiotic (in addition to vitamin C and a multivitamin). I tried colostrum earlier this year, but it made my head feel a lot worse. I would greatly appreciate any suggestions for immune modulators that will bring TH-1 into balance without up-regulating TH-2.