I have been extremely ill. I've been having liver and kidney symptoms for a long time but recently really bad. Weak pulse, low back pain, dark circles under eyes, darker urine, fluid retention, extremely tired, etc. BUN/creatinine always high, liver enzymes going way up and then back down. Now I can no longer take any supplements, shortly after I do my liver starts burning and then shortly after my legs and arms swell and get extremely sore. It's like the liver cannot process anything. After being everywhere looking for answers I had electro dermal screening done and it showed my genes are a factor. It showed sulfation pathway, ammonia, b12, folate, SAMe, urea, taurine, and kidneys to all be a problem. My question is what in the world is going in? Why can't my liver process anything? Why am I unable to take supplements?
Also would my urea cycle and CBS genes benefit from orithine? Should I start on the MTHFR A1298C since I'm most likely completely depleted on BH4?
I had a Nutraeval test done last year and it showed low taurine, and low ammonia in urine so the whole CBS thing throws me off. Is mine active or do I move onto the next step?
Can a lack of vitamins literally make the liver unable to process supplements? Am I just this toxic that my body can't take anymore? I'm miserable and no one has any answers. Liver doctors/methylation doctors/Lyme doctors/naturopaths/homeopaths, etc no one seems to be able to figure this out. There has got to be a reason I got this bad after taking detox drops. It feels like it pulled a bunch of toxins and my liver was unable to excrete it.
Here are my mutations:
ACAT1-02 +\-
CBS A360A +\+
CBS C699T +\-
COMT V158M +\-
COMT H62H +\-
NOS rs1800783 +\+
NOS rs1800779 +\+
NOS1 rs3782206 +\-
NOS3 G10T +\+
NOS3 T786C +\+
MTRR A66G +\-
MTRR 11 A664A +\-
MTHFR 03 P39P +\-
MTHFR A1298C +\-
MTHFR A1572G +\-
MAO A R297R +\-
VDR Taq +\-
Also would my urea cycle and CBS genes benefit from orithine? Should I start on the MTHFR A1298C since I'm most likely completely depleted on BH4?
I had a Nutraeval test done last year and it showed low taurine, and low ammonia in urine so the whole CBS thing throws me off. Is mine active or do I move onto the next step?
Can a lack of vitamins literally make the liver unable to process supplements? Am I just this toxic that my body can't take anymore? I'm miserable and no one has any answers. Liver doctors/methylation doctors/Lyme doctors/naturopaths/homeopaths, etc no one seems to be able to figure this out. There has got to be a reason I got this bad after taking detox drops. It feels like it pulled a bunch of toxins and my liver was unable to excrete it.
Here are my mutations:
ACAT1-02 +\-
CBS A360A +\+
CBS C699T +\-
COMT V158M +\-
COMT H62H +\-
NOS rs1800783 +\+
NOS rs1800779 +\+
NOS1 rs3782206 +\-
NOS3 G10T +\+
NOS3 T786C +\+
MTRR A66G +\-
MTRR 11 A664A +\-
MTHFR 03 P39P +\-
MTHFR A1298C +\-
MTHFR A1572G +\-
MAO A R297R +\-
VDR Taq +\-