Here is my situation. I have a good B-complex in place (thorne basic b's), I am building hydroxyb12 and dibencozide. I got up to 1000mcg of hydroxy and an 1/8th of diben (source naturals not sure of amount). I started feeling really wiped out, hair falling out, spaced out, fatigue all the time. I figured this is from a possibly folate deficiency issue. I have tried to introduce some methylfolate 400mcg plus whats in complex and I get irritable i'm guessing this is from my COMT status. Could these symptoms be anything other than the B12's possibly causing a folate deficiency? Has this happened to anyone and what was your strategy to get around it? Lower b12's until the folate can catch up?