I have been doing a lot of research and want to get some feedback from you guys re: a few potential supplements (and if I try them, it will be low dose and one at a time!) I am tagging a few people @zzz @heapsreal @caledonia @Sushi who might know about these supplements but no pressure to respond and if you don't know the answers, no worries!!! I would love to hear from anyone who has tried these supplements (good or bad.) 1) PQQ or "Pyrroloquinoline Quinone" which is claimed to actually stimulate the growth of new mitochondria and helps mitos to divide into new cells. It also said it is cardio-protective and given after heart attacks similar to a beta blocker. It sounds like a miracle supplement for someone with CFS if true. 2) Alpha Lipoic Acid- It is supposed to help with mitochondria (maybe similar to CoQ10 which I already take) but not sure of the mechanism? 3) B-5 or Pantathenic Acid- I read that it can increase blood pressure which is something I need but will not be relevant for everyone. Someone e-mailed me that it also helped with angina type episodes and I really appreciated that info. I am afraid it could be too stimulating since I seem to have trouble with the B vitamins and this seems to only come in a high dose. Does anyone recommend a specific dose of this? 4) L-Carnitine- I think this is also for mitochondria and to create energy. I tried it 3x about a year ago and had a horrible reaction (severe nausea, insomnia, and felt agitated) but it did give me energy. So, I am now wondering if I tried it at a much lower dose if it could help? I tried 500 mg which was clearly too high but I wonder if I took a micro dose (maybe 50 mg?) how it would be? But if it could give me tachycardia, I do not want to mess with it. Even if you have only tried one of the four, I would love to hear any feedback. Thanks in advance as always!!!