Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Need help with 23andme test results

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by alwayshopeful, Dec 11, 2013.

  1. alwayshopeful

    alwayshopeful

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    Just got my results and its a little confusing to decipher. Don't have a doctor in the area to help me, so thought I would consult with the REAL experts.....you guys!!!!!
     

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  2. alwayshopeful

    alwayshopeful

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    Anyone?? Where do I start??
     
  3. ahmo

    ahmo Senior Member

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    Northcoast NSW, Australia
    Hi always. You might want to start with reviewing the relevant sections from Heartfixer: http://www.heartfixer.com/AMRI-Nutrigenomics.htm

    Your CBS homozygous defect will need to be addressed first. Eliminating sulfur and high thiol vegetables is important. Here are some references: http://livingnetwork.co.za/chelationnetwork/food/high-sulfur-sulphur-food-list/

    I found this conversation very helpful when first coming to terms with sulfur:

    http://www.mothering.com/community/t/1053485/sulfur-sensitivity

    Sulfur-containing drugs: http://www.stuartxchange.org/Sulfa.html

    Another food list: http://www.beatcfsandfms.org/html/Sulfides.html

    Lysine helps detox sulfur from the body. Sorry, that's all I can do for now. If you have reasonable concentration, Amy Yasko's definitive book is available as free ebook. You can use a search function to get what you want. Heartfixer, first link above, is a consolidation of Yasko's info:
    http://www.holisticheal.com/autism-pathways-to-recovery-book-and-workbook.html

    If you go to your profile, you can print your SNPs into your signature, so it's easier for others to see and comment.

    Best to you, ahmo
     
    Last edited: Dec 12, 2013
  4. caledonia

    caledonia

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    Cincinnati, OH, USA
    First off, there is an interpretation on your genetic genie page, you just have to scroll down past your SNPs a little. I wonder how many people are missing this?

    You have three First Priority mutations - SHMT, ACAT and CBS. For SHMT, take folinic acid, for ACAT take bile salts. SHMT and ACAT are called the "leaky gut genes" and people with these mutations can have more problems with their gut. If this is you, do the 4R Gut Rebuilding program (in my signature links), and also treat SHMT and ACAT at the same time.

    For CBS, you have the minor mutation, and no BHMTs, so it's less likely that CBS will be a problem for you. If you have problems tolerating methyl supps, such as a stress/anxiety reaction, or a head pressure, or problems tolerating sulfur foods, supps or meds, then CBS could be expressed. You can do further investigation with testing to confirm. The Heartfixer page has a good CBS program which I've used successfully, except for I used the Free Thiol diet and no Yasko RNA supps.

    You have MTHFR A1298C, so some methylfolate for that. You have MTRR which is B12 recycling, so some B12 for that. For your COMT/VDR combo, Yasko suggests all three types of B12 (hydroxy, methyl and adenosylcobalamin) with less methylcobalamin.

    VDR Bsm is the Vitamin D Receptor, so get your vit D checked and supplement if low.

    MAO A affects serotonin. Yasko suggests waiting until the rest of the cycle is in balance, then if you're still having problems supplement with a low level of 5htp. This is contraindicated if you're on SSRI/SNRI's.

    In general, watch/read all the links in my signature, especially Start Low and Go Slow.
     
  5. Sea

    Sea Senior Member

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    NSW Australia
    I think I read somewhere that Genetic Genie has removed the health interpretation now, but still provides the panel.
     
  6. caledonia

    caledonia

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    Cincinnati, OH, USA
    Nope, I just ran mine through again and it still provides an interpretation along with the panel.
     
    Sea likes this.

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