Hi Sea, No, I don't see from the results in your signature that there are complications to just jumoing in and correcting the deficiencies. Yes, you would have induced deficiencies most likely and deal with a lot of discomforts as things start coming back. I don't agree with what the interpreations are. Predictions made from 60 years of research and experience wirth folic acid, HyCbl and CyCbl in no way predict what happens with AdoCbl, MeCbl and l-methylfolate, with an LCF chaser. You can test the hypothesis very quickly. Of course if one were believe that neurological and mitochondrial and healing startup to be damaging to themself then they wouldn't correctly interpret the clues. People's working hypothesis controls what they try. When what can work appears counterintuitive to people they tend to avoid it.