Looking Ahead to Change: Little by Little
I don't make New Year's Resolutions. I don't think I ever really did, but the last decade or two would have been enough to stifle that impulse. I've just been too aware that I don't have that much control over what happens in my life.
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Need Assistance with results ...

Discussion in 'Genetic Testing and SNPs' started by Bosco, Oct 22, 2014.

  1. Bosco

    Bosco

    Messages:
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    Can anyone assist me with these results? With my limited knowledge I would have to guess that my methylation is fairly poor.

    Health issues experienced at times

    Strong anxiety / panic attacks
    Chronic Fatigue, regardless of amount of sleep
    Sexual "issues"
    Poor sleep / night waking


    Maybe someone can make sense of this? Thanks in advance.


    Some of it is a bit concerning particularly:

    COMT V158M rs4680 AA +/+ (4 COMT mutations = dopamine issue?)
    COMT H62H rs4633 TT +/+

    MTHFR C677T rs1801133 AA +/+
    CBS C699T rs234706 AA +/+
    BHMT-08 rs651852 TT +/+


    CYP1B1 L432V rs1056836 GG +/+ (4 CYP1B1 mutations = Estrogen Issue?)
    CYP1B1 R48G rs10012 CC +/+

    Gene & VariationrsIDAllelesResult
    COMT V158M rs4680 AA +/+
    COMT H62H rs4633 TT +/+

    COMT P199P rs769224 GG -/-
    VDR Bsm rs1544410 CC -/-
    VDR Taq rs731236 AA +/+
    MAO A R297R rs6323 G -/-
    ACAT1-02 rs3741049 GG -/-
    MTHFR C677T rs1801133 AA +/+
    MTHFR 03 P39P rs2066470 GG -/-
    MTHFR A1298C rs1801131 TT -/-
    MTR A2756G rs1805087 AA -/-
    MTRR A66G rs1801394 AG +/-
    MTRR H595Y not found
    MTRR K350A rs162036 AG +/-
    MTRR R415T not found
    MTRR A664A rs1802059 GG -/-
    BHMT-02 rs567754 CC -/-
    BHMT-04 not found
    BHMT-08 rs651852 TT +/+
    AHCY-01 rs819147 CT +/-
    AHCY-02 not found
    AHCY-19 rs819171 CT +/-
    CBS C699T rs234706 AA +/+
    CBS A360A rs1801181 GG -/-
    CBS N212N not found
    SHMT1 C1420T not found
    Profile: Methylation Profile
    Generated: 10/22/2014
    Download this report as a PDF:


    Gene & Variation rsID Alleles Result

    CYP1A1*2C A4889G rs1048943 TT -/-
    CYP1A1 m3 T3205C rs4986883 TT -/-
    CYP1A1 C2453A rs1799814 GG -/-
    CYP1A2 164A>C rs762551 AA -/-
    CYP1B1 L432V rs1056836 GG +/+
    CYP1B1 N453S rs1800440 TT -/-
    CYP1B1 R48G rs10012 CC +/+
    CYP2A6*2 1799T>A rs1801272 AA -/-
    CYP2A6*20 rs28399444 II -/-
    CYP2C9*2 C430T rs1799853 CT +/-
    CYP2C9*3 A1075C rs1057910 AA -/-
    CYP2C19*17 rs12248560 CC -/-
    CYP2D6 S486T rs1135840 CG +/-
    CYP2D6 100C>T rs1065852 GG -/-
    CYP2D6 2850C>T rs16947 AG +/-
    CYP2E1*1B 9896C>G rs2070676 CC -/-
    CYP2E1*1B 10023G>A rs55897648 GG -/-
    CYP2E1*4 4768G>A rs6413419 GG -/-
    CYP3A4*1B rs2740574 TT -/-
    CYP3A4*2 S222P rs55785340 AA -/-
    CYP3A4*3 M445T rs4986910 AA -/-
    CYP3A4*16 T185S rs12721627 GG -/-
    GSTP1 I105V rs1695 AA -/-
    GSTP1 A114V rs1138272 CC -/-
    SOD2 A16V rs4880 AA -/-
    NAT1 R187Q rs4986782 GG -/-
    NAT1 R64W rs1805158 CC -/-
    NAT2 I114T rs1801280 CT +/-
    NAT2 R197Q rs1799930 GG -/-
    NAT2 G286E rs1799931 GG -/-
    NAT2 R64Q rs1801279 GG -/-
    NAT2 K268R rs1208 GG +/+


    Sterling App

    DETOX
    Gene & VariationrsID #Risk AlleleYour Alleles & Results
    CYP1A1*2C A4889G rs1048943 C TT -/-
    CYP1A1*4 C2453A rs1799814 T GG -/-
    CYP1A2 C164A rs762551 C AA -/-
    CYP1B1 L432V rs1056836 C GG -/-
    CYP1B1 N453S rs1800440 C TT -/-
    CYP1B1 R48G rs10012 C CC +/+
    CYP2A6*2 A1799T rs1801272 T AA -/-
    CYP2C19*17 rs12248560 T CC -/-
    CYP2C9*2 C430T rs1799853 T CT +/-
    CYP2C9*3 A1075C rs1057910 C AA -/-
    CYP2D6 S486T rs1135840 G CG +/-
    CYP2D6 T100C rs1065852 A GG -/-
    CYP2D6 T2850C rs16947 A AG +/-
    CYP2E1*1B G9896C rs2070676 G CC -/-
    CYP2E1*4 A4768Grs6413419AGG-/-
    CYP3A4*1Brs2740574CTT-/-
    CYP3A4*3 M445Trs4986910GAA-/-
    GPX3rs8177412C
    GSTM1rs12068997T
    GSTM1rs4147565A
    GSTM1rs4147567G
    GSTM1rs4147568A
    GSTM1rs1056806TCC-/-
    GSTM1rs12562055A
    GSTM1rs2239892G
    GSTP I105Vrs1695GAA-/-
    GSTP1 A114Vrs1138272TCC-/-
    NAT1 A560G(?) (R187Q)rs4986782AGG-/-
    NAT2 A803G (K268R)rs1208GGG+/+
    NAT2 C190T (R64W)rs1805158TCC-/-
    NAT2 G590A (R197Q)rs1799930AGG-/-
    NAT2 G857A (G286E)rs1799931AGG-/-
    NAT2 T341C (I114T)rs1801280CCT+/-
    SOD2rs2758331ACC-/-
    SOD3rs2855262TTT+/+
    SOD2 A16Vrs4880GAA-/-
    PON1 Q192Rrs662CCC+/+

    TONGUE TIE / CLEFT PALATE

    CTH S4031Irs1021737TGG-/-
    IRF6rs987525ACC-/-
    IRF6rs861020AGG-/-
    RARArs7217852GAA-/-
    RARArs9904270T
    TBX22rs41307258AT-
    TBX22rs28935177TA-

    ALLERGY/MOLD

    HLArs7775228CTT-/-
    HLArs2155219TGG-/-

    IgE

    FCER1Ars2427837A
    IL-13 C1112Trs1800925TCT+/-
    DARCrs2814778CTT-/-
    IL13rs1295685A
    CD14rs2569191CCT+/-
    SOCS-1 -820G>Trs33977706AAC+/-
    C3rs366510G
    FCER1A / OR10J2Prs2494262A
    FCER1Ars2251746CCT+/-
    RAD50rs2040704GAG+/-
    RAD50rs2240032TCT+/-

    IgG

    FCGR2Ars1801274AGG-/-
    GSTM3 V224Irs7483TTT+/+
    TNFRSF13Brs4792800G

    IgA

    TRAF1rs3761847GGG+/+
    IRF5rs4728142AAA+/+
    IGF1Rrs2229765AAG+/-
    IFIH1 (HLA)rs1990760CCC+/+
    HLArs9271366GAA-/-
    CFHrs6677604AAG+/-
    HLA-DQA2rs9275224AAA+/+
    MTC03P1rs9275596CCT+/-
    PSMB8 / TAP1 / TAP2rs9357155AGG-/-
    HLA-DPB2 / COL11A2Prs1883414AAG+/-

    CLOTTING FACTORS

    CETPrs1800775CCC+/+
    CYP4V2rs13146272CCC+/+

    GP6rs1613662GAG+/-
    ITGB3 T196Crs5918CCT+/-
    KNG I598Trs2731672TCC-/-
    NR1I2rs1523127CAC+/-
    SERPINC1rs2227589TCC-/-
    HRGrs9898TCC-/-
    F12rs1801020A
    F11rs2289252TTT+/+
    F11rs2036914T
    F10 113777509rs3211719GAA-/-
    F7 A353Grs6046AAG+/-
    F2 (Prothrombin 20210A)i3002432AGG-/-
    F3 94997288rs1324214A
    F5 (Factor V Leiden)rs6025TCC-/-
    F9 G580Ars6048GA-

    METHYLATION

    ACE Del16rs4343GAG+/-
    ADD1 G460Wrs4961TGG-/-
    ACAT1-02rs3741049AGG-/-
    AGT M235T/C4072Trs699GAG+/-
    AHCY-01rs819147CCT+/-
    AHCY-02rs819134G
    AHCY-19rs819171CCT+/-
    BHMTrs16876512T
    BHMTrs6875201GAA-/-
    BHMT-02rs567754TCC-/-
    BHMT-04rs617219C
    BHMT-08rs651852TTT+/+
    BHMT R239Qrs3733890AGG-/-
    CBS A13637Grs2851391TTT+/+
    CBS A360Ars1801181AGG-/-
    CBS C19150Trs4920037AAA+/+
    CBS C699Trs234706AAA+/+

    CBS N212Nrs2298758A
    COMTrs6269GAA-/-
    COMT -61 P199Prs769224AGG-/-
    COMT H62Hrs4633TTT+/+
    COMT V158Mrs4680AAA+/+

    DAOrs2070586AGG-/-
    DAOrs2111902G
    DAOrs3741775CAC+/-
    DHFRrs1643649CTT-/-
    FOLR1rs2071010AGG-/-
    FOLR2rs651933AAG+/-
    FOLR3rs7925545GAA-/-
    FOLR3rs7926875A
    FUT2rs492602GAA-/-
    FUT2rs601338AGG-/-
    FUT2rs602662AAG+/-
    G6PDrs1050828TC-
    G6PDrs1050829CT-
    GAD1rs3749034AGG-/-
    GAD1rs2241165CTT-/-
    GAD1rs769407CCC+/+
    GAD1rs2058725CTT-/-
    GAD1rs3791851CCC+/+
    GAD1rs3791850AGG-/-
    GAD1rs12185692ACC-/-
    GAD1rs3791878TTT+/+
    GAD1rs10432420AGG-/-
    GAD1rs3828275TCC-/-
    GAD1rs701492TTT+/+
    GAD1rs769395G
    GAD2rs1805398T
    GAMTrs17851582AGG-/-
    GAMTrs55776826TCC-/-
    GIF (TCN3)rs558660AGG-/-
    MAO A R297Rrs6323TG-
    MAT1Ars72558181T
    MTHFD1 C105Trs1076991CCT+/-
    MTHFD1 G1958Ars2236225AGG-/-
    MTHFD1Lrs11754661AGG-/-
    MTHFD1Lrs17349743CCT+/-
    MTHFD1Lrs6922269AAG+/-
    MTHFD1Lrs803422AGG-/-
    MTHFR 03 P39Prs2066470AGG-/-
    MTHFR A1298Crs1801131GTT-/-
    MTHFR A1572Grs17367504GAA-/-
    MTHFR C677Trs1801133AAA+/+
    MTHFR G1793A (R594Q)rs2274976TCC-/-
    MTHFRrs12121543A
    MTHFRrs13306560TCC-/-
    MTHFRrs13306561G
    MTHFRrs1476413TCC-/-
    MTHFRrs17037390AGG-/-
    MTHFRrs17037396T
    MTHFRrs3737964TCC-/-
    MTHFRrs4846048GAG+/-
    MTHFRrs4846049TGG-/-
    MTHFSrs6495446CCC+/+
    MTR A2756Grs1805087GAA-/-
    MTRR A66Grs1801394GAG+/-
    MTRR H595Yrs10380T
    MTRR K350Ars162036GAG+/-
    MTRR R415Trs2287780T
    MTRR-11 A664Ars1802059AGG-/-
    MTRRrs10520873C
    MTRRrs1532268TCC-/-
    MTRRrs162049G
    MTRRrs3776467GAG+/-
    MTRRrs9332AAG+/-
    NOS1rs3782206T
    NOS2rs2297518AAG+/-
    NOS2rs2274894TGT+/-
    NOS2rs2248814AAG+/-
    NOS3rs1800783ATT-/-
    NOS3rs1800779GAA-/-
    NOS3rs3918188AAC+/-
    NOS3 G10Trs7830T
    NOS3 T786Crs2070744C
    PEMTrs4244593TGT+/-
    PEMTrs4646406AAT+/-
    PEMTrs7946CCT+/-
    SHMT1 C1420Trs1979277A
    SHMT1rs9909104C
    SHMT2rs12319666T
    SHMT2rs34095989AAG+/-
    SLC19A1rs1888530T
    SLC19A1rs3788200A
    TCN1rs526934GAA-/-
    TCN2 C766Grs1801198GCC-/-
    TYMSrs502396C
    VDR Bsmrs1544410TCC-/-

    CELIAC DISEASE/GLUTEN INTOLERANCE

    HLArs2858331GAA-/-
    HLA DQA1rs2187668TCT+/-

    THYROID

    CTLA4rs231775GAG+/-
    FOXE1rs1867277AGG-/-
    FOXE1rs7043516C
    FOXE1rs10984009AGG-/-
    EYE HEALTH
    Gene & VariationrsID #Risk AlleleYour Alleles & Results
    BCMO1rs4889294CTT-/-
    BCMO1 R267Srs12934922TAA-/-
    BCMO1 A379Vrs7501331TTT+/+

    MITOCHONDRIAL FUNCTION

    ATP5g3rs185584G
    ATP5g3rs36089250CTT-/-
    ATP5c1rs2778475A
    ATP5c1rs1244414TCT+/-
    ATP5c1rs1244422T
    ATP5c1rs12770829T
    ATP5c1rs4655C
    COX5Ars8042694GAA-/-
    COX6Crs4626565CCC+/+
    COX6Crs7844439A
    COX6Crs4510829A
    COX6Crs1135382A
    COX6Crs7828241C
    COX6Crs12544943G
    COX6Crs4518636C
    NDUFS3rs2233354C
    NDUFS3rs4147730AAG+/-
    NDUFS3rs4147731A
    NDUFS7rs2332496AAA+/+
    NDUFS7rs7254913G
    NDUFS7rs1142530TTT+/+
    NDUFS7rs7258846TTT+/+

    NDUFS7rs11666067A
    NDUFS7rs2074895A
    NDUFS7rs809359GAA-/-
    NDUFS8rs4147776C
    NDUFS8rs1122731A
    NDUFS8rs999571AGG-/-
    NDUFS8rs2075626CTT-/-
    NDUFS8rs3115546G
    NDUFS8rs1104739C
    NDUFS8rs1051806TCC-/-
    UQCRC2rs6497563C
    UQCRC2rs4850AGG-/-
    UQCRC2rs11648723T
    UQCRC2rs12922362A
    UQCRC2rs2965803T

    OTHER IMMUNE FACTORS

    4q27 Regionrs6822844TGG-/-
    APOErs429358CTT-/-
    ATG16L1rs10210302TCT+/-
    GSDMBrs7216389TCT+/-
    HLA-DRB1rs660895GAA-/-
    IL5rs2069812AGG-/-
    IL-13rs20541AAA+/+
    IL4R Q576Rrs1801275GAA-/-
    MeFV A744Si4000409ACC-/-
    MeFV E148Qrs3743930GCC-/-
    MeFV F479Li4000403CGG-/-
    MeFV K695Ri4000407CTT-/-
    MeFV M680Irs28940580GCC-/-
    MeFV M694Irs28940578TCC-/-
    MeFV M694Vi4000406CTT-/-
    MeFV P369Srs11466023AGG-/-
    MeFV R761Hi4000410TCC-/-
    STAT4rs10181656GCC-/-
    TNF -308rs1800629AAG+/-
    TNF -238rs361525AGG-/-
    TYR (MeFV) V726Ars28940879AGG-/-

    SULFONOTRANSFERASE

    SULT1A1rs35728980GGT+/-
    SULT1A1rs1801030C
    SULT1A1rs1042157AAG+/-
    SULT1A1rs36043491TCC-/-
    SULT1A1rs60749306CTT-/-
    SULT1A1rs9282862CTT-/-
    SULT1A1rs1042008AGG-/-
    SULT1A1rs2925627C
    SULT1A1rs2925631C
    SULT1A1rs3020800G
    SULT1A1rs4149385TCC-/-
    SULT1A1rs60701883ACC-/-
    SULT1A1rs4149381GTT-/-
    SULT1A1rs8057055A
    SULT1A1rs6498090A
    SULT1A1rs7193599C
    SULT1A1rs7192559TCC-/-
    SULT1A3rs1059667A
    SULT2A1rs296366TCT+/-
    SULT2A1rs296365C
    SULT2A1rs11569679TCC-/-
    SULT2A1rs4149452TCC-/-
    SULT2A1rs8113396G
    SULT2A1rs2547242C
    SULT2A1rs2910393T
    SULT2A1rs4149449TCC-/-
    SULT2A1rs2547231CAC+/-
    SULT2A1rs4149448G
    SULT2A1rs11083907AGG-/-
     
    Last edited: Oct 23, 2014

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