I started Equilibrant about 4 months ago. I had a very hard time with extreme fatigue even with the first pill. I worked my way up to 4 in 4 weeks, but it was too much to handle so I backed down to 2. I stayed at 2 for another month and a half, felt OK, then started on 3, then 4 a couple weeks later. I had bad startup effects with 3 and felt achy, but when that started to die down a bit I went up to 4 and have been flu-y and achy for a solid week now. It's getting just a little better each day, but it is still rough. So, I'm trying to determine whether I should just stick it out and stay on 4, or back down to 3 for a while. I know that having these symptoms is actually a good sign and means it is probably working. But it is rough going. I'm willing to just go with it and feel crappy for a while if need be, but I'm unsure whether that is the right approach. Obviously I have no doctor to consult with about this. Those of you with experience, what do you recommend? Ride it out for as long as it takes and just feel bad, or back down? I don't want to lose the progress I've made upping the dose, but I'm suffering.