I am homozygous MTHFR mutation and I have CFIDS/ME, POTS, etc. I've been feeling really depressed and my neuroadrenal levels were through the roof, showing high everything (from serotonin to cortisol). My doctor concluded I"m in a constant state of high anxiety and stress that is wiping me out. She suggested taking a combo of folinic acid and b12 and thought this would help with the depression. The folinic acid though (800mcg) is giving me headaches and making me feel crappy. I have a prescription of potassium but I never take it because I'm afraid of it - I know this is a bit silly but my heart just feels so unstable and I've read scary things about potassium and the heart. My cardiologist was the one who prescribed it for me so even sillier. But I'm on SOOO many medications and supplements that I try to introduce new things one at a time and very slowly. Should I be taking this with the folinic acid? Will it help alleviate the negative side effects? I'm really struggling to wrap my head around all of this, especially with the brain fog and general depletion. Anyone who can give me a quick laymen's terms guide would be so appreciated. Thank you!