New Atmosphere, New Vision: Gibson and Whittemore Kick Off Invest in ME Conference 2016
Mark Berry reports on Dr. Gibson's introduction and Dr. Whittemore's keynote speech, at the 11th Invest in ME International ME Conference in London.
Discuss the article on the Forums.

Naviaux et. al.: Metabolic features of chronic fatigue syndrome

Discussion in 'Latest ME/CFS Research' started by A.B., Aug 29, 2016.

  1. A.B.

    A.B. Senior Member

    Messages:
    3,002
    Likes:
    16,973
    The Naviaux study we have been waiting for

    Metabolic features of chronic fatigue syndrome


    http://www.pnas.org/content/early/2016/08/24/1607571113.long
     
    Joh, Stretched, brokenmito and 69 others like this.
  2. Ben Howell

    Ben Howell OMF Correspondent

    Messages:
    556
    Likes:
    6,101
    U.K.
    Hot off the press! Nice one!

    Unbelievably significant.

    It's gonna go off!


    B
     
    Last edited: Aug 29, 2016
    Jennifer J, Advocate, moosie and 11 others like this.
  3. gregh286

    gregh286 Senior Member

    Messages:
    508
    Likes:
    580
    Londonderry, Northern Ireland.
    Stress induced metabolic pathway alterations. Wow
     
  4. A.B.

    A.B. Senior Member

    Messages:
    3,002
    Likes:
    16,973
    This is half the answer. The other half is figuring out why this state persists for so long.

    It feels like we're really close to understanding this disease. And once you understand the problem, coming up with a treatment could be quite simple.
     
    Joh, LSLJ, brokenmito and 33 others like this.
  5. charles shepherd

    charles shepherd Senior Member

    Messages:
    1,744
    Likes:
    10,854
  6. snowathlete

    snowathlete

    Messages:
    3,069
    Likes:
    11,938
    UK
    Joh, L'engle, Wolfiness and 16 others like this.
  7. Ben Howell

    Ben Howell OMF Correspondent

    Messages:
    556
    Likes:
    6,101
    U.K.
    "Area under the receiver operator characteristic curve analysis showed diagnostic accuracies of 94% [95% confidence interval (CI), 84–100%] in males using eight metabolites and 96% (95% CI, 86–100%) in females using 13 metabolites."
     
    Barry53, L'engle, PennyIA and 10 others like this.
  8. snowathlete

    snowathlete

    Messages:
    3,069
    Likes:
    11,938
    UK
    UK psychiatrist (who is commenting on CFS story, why?) says a lot more work to be done yet, well there was my second shock.
     
    Joh, L'engle, Advocate and 8 others like this.
  9. dancer

    dancer Senior Member

    Messages:
    267
    Likes:
    768
    Midwest, USA
    Why on earth did the daily mail interview a psychiatrist for comment? And when will we stop being besieged by the "this might show it's not all in the mind" narratives? How many times must that be shown before that stops being the go-to focus? Sigh.

    But the study does sound intriguing. My brain can't quite follow it all...so I'm hoping for analysis from all the great science minds on this forum.
     
    Helen, Joh, Keela Too and 23 others like this.
  10. Sidereal

    Sidereal Senior Member

    Messages:
    2,996
    Likes:
    16,194
    Who is this randomer from Edinburgh and why is he of all the people in the world being asked to opine on a metabolomics study?
     
    Joh, J.G, picante and 16 others like this.
  11. Sidereal

    Sidereal Senior Member

    Messages:
    2,996
    Likes:
    16,194
    Might be worth adding Naviaux to the thread title, lots of people have been anticipating the publication of his study and the title of the paper is a little vague.
     
    L'engle, Advocate, Solstice and 6 others like this.
  12. Cheshire

    Cheshire Senior Member

    Messages:
    878
    Likes:
    5,701
    France
    gretac, Harown, L'engle and 18 others like this.
  13. Groggy Doggy

    Groggy Doggy Mermaid.....lost on land

    Messages:
    668
    Likes:
    1,606
    USA
    PDF version
     

    Attached Files:

    L'engle, Advocate, Solstice and 10 others like this.
  14. deleder2k

    deleder2k Senior Member

    Messages:
    1,030
    Likes:
    4,362
    What will the psychobabblers say about this study? That the proposed test isn't worth anything because we don't know if people that are depressed or that have other diseases carry the same abnormalities..?
     
    L'engle, Advocate and Hutan like this.
  15. alex3619

    alex3619 Senior Member

    Messages:
    11,767
    Likes:
    30,486
    Logan, Queensland, Australia
    Not like a rocket, more like a TARDIS!!!
     
    gretac, George, temple88 and 16 others like this.
  16. Ben Howell

    Ben Howell OMF Correspondent

    Messages:
    556
    Likes:
    6,101
    U.K.
    This is being addressed as part of OMF's future study i.e checking the biochemical 'signature' against other illnesses.


    B
     
    L'engle, Advocate, caledonia and 15 others like this.
  17. deleder2k

    deleder2k Senior Member

    Messages:
    1,030
    Likes:
    4,362
    Like this?? [​IMG]
     
    gretac, temple88, L'engle and 11 others like this.
  18. Ben Howell

    Ben Howell OMF Correspondent

    Messages:
    556
    Likes:
    6,101
    U.K.
    Would like to hear your thoughts on it @alex3619.


    B
     
    Advocate, TiredSam and deleder2k like this.
  19. Bob

    Bob

    Messages:
    12,422
    Likes:
    37,466
    England (south coast)
    Weblink to download the PDF (early version) from the website:
    http://www.pnas.org/content/early/2016/08/24/1607571113.full.pdf

    It's best to download the PDF from the website, for two reasons:
    1. To get the latest version. (With edits and corrections etc.)
    2. So that the journal gets to count the download hits.
     
  20. gregh286

    gregh286 Senior Member

    Messages:
    508
    Likes:
    580
    Londonderry, Northern Ireland.
    lipid groups with over 80% metabolic impact in the study.
     
    Gondwanaland and Advocate like this.

See more popular forum discussions.

Share This Page