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Natural supplements that can stop Dopamine's conversion to Norepinephrine?

Discussion in 'Adrenal Dysfunction' started by Peyt, Dec 17, 2015.

  1. Peyt

    Peyt Senior Member

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    Is there any natural supplements that can stop Dopamine's conversion to Norepinephrine?
     
    kjellfh likes this.
  2. Peyt

    Peyt Senior Member

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    Although I have not found anything specific since I put up this post, I did learn that Lithium can lower Norepinephrine while increasing Serotonin.
     
  3. Peyt

    Peyt Senior Member

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    I am replying to my old thread again just because I think this is key info for someone suffering with anxiety created by excess NE.. Magnesium can help with this process a lot.
     
  4. aaron_c

    aaron_c Senior Member

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    Excessive copper can increase the conversion of dopamine to norepinephrine through increases (in number or function?) of dopamine beta-hydroxylase, a copper-containing enzyme. When I took copper, one of the things that happened was my mental focus improved while my motivation just kind of petered out. I assume that was from plenty of NE, but not enough dopamine.
     
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  5. Tunguska

    Tunguska Senior Member

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    I want to know this too, due to problems with high NE/low DA (this is a simplification).

    Like Aaron said, copper fed to animals increased NE and likely can do the same in people in large doses.

    Vit C is the other cofactor, but it's less clear its effects. I do avoid large doses.

    There's a thread on longecity: http://www.longecity.org/forum/topi...ine-if-you-got-issues-decrease-noradrenaline/

    Disulfiram is out of the picture for obvious reasons. The most interesting was Ursolic Acid: https://www.ncbi.nlm.nih.gov/pubmed/24116298 (credit to longecity)
    But the supplement Ursolic acid seems to be unaffordable in high doses and bodybuilders don't report much from it. I doubt 50mg in Fuji apples amounts to much.
     
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  6. aaron_c

    aaron_c Senior Member

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    Hah. I didn't say that, exactly. Actually, I was having trouble finding a study to back up what I have thought for a few years to be true. Thanks!
     
  7. Tunguska

    Tunguska Senior Member

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    Sorry, I took a verbal shortcut. This is one: https://www.ncbi.nlm.nih.gov/pubmed/11048941
     
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  8. Peyt

    Peyt Senior Member

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    If this is true, it makes sense why my body resonates with Molybdenum so much. It pulls copper.
    I thought the reason I do well with Molybdenum is because it cleans out the Sulfites. But whatever, it works for me! :)
     
    Paralee likes this.

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