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National Institute of Allergy and Infectious Diseases Job Advert

Discussion in 'XMRV Research and Replication Studies' started by Katie, Feb 11, 2010.

  1. Katie

    Katie Guest

    My good friend Agent Joyscobby found this little gem :Retro wink:

    http://jobs.phds.org/job/18112/nati...asis-of-resistance-to-mouse-gammaretroviruses

    Check out the current research they want to link in with, there's a lot of interesting gammaretroviral work going on that could help us. This is not CFS or XMRV specific but it does include XMRV and inhibiting replication of these slow retroviruses which can only help us. I won't read too much into this but it looks more likely that XMRV is being found to be pathogenic to some degree, whether it be prostate cancer or CFS to have reason to want to know how to stop it replicating. It's a nice little find by Joy.


    Genetic Basis of Resistance to Mouse Gammaretroviruses, Dr. Christine Kozak
    Description:

    A postdoctoral position is available in the Viral Biology Section of the Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases in a program that is focused on factors that inhibit gammaretrovirus replication at entry or post-entry stages of the viral life cycle. Recent and ongoing projects include: 1) the identification of receptor determinants for xenotropic gammaretroviruses including XMRV, an isolate from human prostate cancers and patients with chronic fatigue syndrome; 2) the co-evolution of xenotropic virus envelope and host receptor in rodent species; 3) the origin and adaptive evolution of post-entry factors in host cells that restrict replication; 4) receptor-mediated control of host range and cytopathicity of ecotropic gammaretroviruses.

    Interested candidates must possess a Ph.D. and/or an M.D. and have a strong background in molecular biology, biochemistry, and/or virology. The salary range is commensurate with experience. To apply, click on the button below, or send a cover letter, curriculum vitae, bibliography, and names of three references to:

    Dr. Christine A. Kozak
    Viral Biology Section, Laboratory of Molecular Microbiology
    National Institute of Allergy and Infectious Diseases
    4 Center Drive MSC0460
    Building 4, Room 329
    Bethesda, MD 20892-0460

    Fax: (301) 402-6447
    E-mail: ckozak@niaid.nih.gov
    Web site: http://www3.niaid.nih.gov/labs/aboutlabs/lmm/viralBiologySection/


    Selected recent publications:

    1. YAN, Y., LIU, Q., AND KOZAK, C. A.: Six host range variants of the xenotropic/polytropic gammaretroviruses define determinants for entry in the XPR1 receptor. Retrovirology 6:87.

    2. KNOPER, R. C., FERRARONE, J., YAN, Y., LAFONT, B. A., AND KOZAK, C. A.: Removal of either N-glycan site from the envelope receptor binding domain of Moloney and Friend but not AKV mouse ecotropic gammaretroviruses alters receptor usage. Virology 391:232-9, 2009.

    3. YAN, Y., BUCKLER-WHITE, A., WOLLENBERG, K, AND KOZAK, C. A.: Origin, antiviral function and evidence for positive selection of the gammaretrovirus restriction gene Fv1 in the genus Mus. Proc. Natl. Acad. Sci. USA. 106:3259-63, 2009.

    4. STOCKING, C. AND KOZAK, C. A.: Murine endogenous retroviruses. Cell. Mol. Life Sci. 65:3383-98, 2008.

    5. YAN, Y. AND KOZAK, C. A.: Novel post-entry resistance to AKV ecotropic mouse gammaretroviruses in the African pygmy mouse, Mus minutoides. J. Virol. 82:6120-9, 2008.

    6. YAN, Y., JUNG, Y. T., WU, T., AND KOZAK, C. A.: Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses. Retrovirology 5:2, 2008.

    7. YAN, Y., KNOPER, R. C., AND KOZAK, C. A.: Wild mouse variants of envelope genes of xenotropic/polytropic mouse gammaretroviruses and their XPR1 receptors elucidate receptor determinants of virus entry. J. Virol. 81:10550-7, 2007.

    8. WU, T., YAN, Y., AND KOZAK, C. A.: Rmcf2, a xenotropic provirus in the Asian mouse species Mus castaneus, blocks infection by polytropic mouse gammaretroviruses. J. Virol. 79:9677-9684, 2005.

    9. JUNG, Y. T., WU, T., AND KOZAK, C. A.: Novel host range and cytopathic variant of ecotropic Friend murine leukemia virus. J. Virol. 78:12189-12197, 2004.


    The NIH is dedicated to building a diverse community in its training and employment programs.
  2. natasa778

    natasa778 Senior Member

    Messages:
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    London UK
    In her Prohealth talk Judy M did mention National Institute of Allergy and Infectious Diseases, didn't she. As in: dozens of places and federal agencies have contacted us and want to collaborate, apart from nihid ... we have yet to hear from them...
  3. Koan

    Koan Be the change.

    Messages:
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    Look at all these crazy scientists carrying on with this research as though it were sensible, solid and sound ;)
  4. Adam

    Adam *****

    Messages:
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    Sheffield UK
    Crazy Scientists

    I love those crazy scientists:Sign Good Job:white coats, 3000 volt hair do's - test tubes, bunsen burners, hi-tech equipment in vast labs wearing goggles and intelligent expressions, talking all technical - and getting excited about it...and not a couch:sofa: in sight.
  5. Koan

    Koan Be the change.

    Messages:
    2,598
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    55
    Seems only fair and right to get professor Weasely's reaction...


    young_frankenstein1.jpg
  6. Katie

    Katie Guest

    And how does that make you feel, Adam? :Retro wink:



    EDIT: Just seen Koan's picture, roflcopter!
  7. LOLLZERS!
    This thread is wonderful, exciting and funny too. It's like the most perfectest thread everrrrr.
    Cheers Katie and Agent Scobby for sponsoring it ;) can I borrow your roflcopter?
    And Koan, love the pic...

    Rachel xx

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