Yes, I agree, it's better to try one thing at a time. It's also helpful to keep a symptom journal where you note what you started and when and then any symptoms good or bad. Start with low doses and increase gradually only if tolerated. This is called Start Low and Go Slow. Here are a couple other simple things you can try for sleep and anxiety. One is to take some magnesium. Any form except magnesium oxide, which doesn't absorb well, is ok. So magnesium citrate, taurate or glycinate, etc. The other one is to work on GABA/glutamate balance. They're neurotransmitters. GABA is calming, while glutamate is stimulating and can cause anxiety. You can take GABA, theanine or other calming supplements while reducing glutamate in the diet. Artificial glutamate, aka MSG, is added to a lot of processed food, and it's hidden with alternative names. It's easier to just avoid processed foods. Then there are 4 foods which are naturally high in glutamates which are peas, tomatoes, mushrooms and Parmesan cheese. If glutamate is one of your problems, and you do the above, you should be feeling better within a week or so. Here is a link to more detailed info: http://www.dramyyasko.com/resources/autism-pathways-to-recovery/chapter-4/ The good info is towards the bottom under the heading "Maintaining a Health Glutamate/GABA Balance". This is actually the first step in a Yasko type methylation protocol, but you don't need any testing to do it.