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N-Acetyl Cysteine?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Vanguard, Aug 26, 2011.

  1. richvank

    richvank Senior Member

    Hi, all.

    Note that the leading cause for liver transplants is overdose of acetaminophen (paracetamol, Tylenol). Some of these overdoses are unfortunately intentional. Also unfortunately, some are not. People who have low glutathione status (such as PWMEs) should probably be especially careful not to overdo taking this drug.

    Best regards,

  2. leokitten

    leokitten Senior Member

    Here's a good recent review paper on NAC research, it's derivatives (such as NACA and NAC ethyl ester), and use in neurological disorders.

    N-acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities

    You aren't the only one who's unclear whether NAC cross the BBB, so is the research community as shown in this paper.

    I also would like to try NACA and think it would make for a good study in ME/CFS.

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