I am currently in the process of researching and testing whether I have a breakdown in my methylation cycle. In addition to my regular long list of symptoms, I have a strange symptom that no one has ever heard of or experienced. In all my research I have never heard it mentioned except for in this one forum http://www.steadyhealth.com/Bruised_feeling_all_over_body_after_drinking_alcohol_t132901.html. But everyone on this page is describing exactly what happens to me too. When I drink alcohol, more particular if I drink more than 2 drinks or over consume, the next day my whole body feels sore and bruised to the touch. It is especially bad around my chest and upper arms, but it is usually all over. It does not happen immediately, and I do not have any of the typical alcohol intolerance symptoms like flushing, itching, dizziness or nausea/vomiting. I feel fine when I am consuming it, and strangely I often feel fine when I get up in the morning. It starts later in the day of the following day, I feel like I am getting the flu because my skin hurts everywhere to the touch. Sometimes it hurts to lay down. The day following that (48 hours) I usually always wake up with swelling and inflammation all over and in my face. Obviously I control this by just avoiding alcohol, but its such and odd and rare symptom I keep feeling like answering this mystery might shed light on some of my other symptoms. Could this be related to an impaired methylation cycle and I am just not able to break it down?