Just want to pick your brains before posting an update on 5-HTP in another thread. What dose were you taking? Were there any other active ingredients? How long had you been taking it before you got the depersonalisation? How long did the depersonalisation last, or did you stop the 5-HTP after it happened? Were there any other symptoms that you describe as depersonalisation, or just the waking up in panic? Thanks. I think I am getting a little mood improvement, which started after a couple of weeks, but there were 2 or 3 days when I felt slightly weird just before the improvement.