After several months on LDN and inosine, my EBV levels actually went up. Thus, I am beginning Famvir as per my ME/CFS specialist. My dose will be 250mg bid for 2 weeks, and then we will raise the dose depending on how I'm feeling. I know this has been discussed to death, but I don't understand the IgG vs IgM (?) argument. My nephrologist looked at my EBV labs today and basically said my ME doc doesn't know what they're doing by putting me on Famvir because there's no way I have EBV (….. everyone has elevated levels, etc). Because Famvir is potentially nephrotoxic, his comments left me confused and scared. If anyone could summarize their experiences with Famvir, including dosages, how often you raised your dose, how long before you saw improvements, etc I would appreciate it deeply. Thanks.