I am taking ALA according to Cutler's recommendations: 50mg every 3hrs for 3 days a week, initially for mercury chelation, now as a cheap anti-retroviral. I have marked improvement, plus some negatives. Is anyone else on it? I would like to hear your experiences? I have noticed the following benefits: Immediate: Improved sleep Dramatic reduction in depression After 3 months No depression at all Less bloating and reflux - able to reduce Zantac by half, although not every time. Small improvement in energy, maybe 10%, but its consistent and steadily improving Doing more things - bit hard to explain because this is not the same as energy increase - eg couldn't contemplate doing tax, now can do it easily Negatives On the days I'm taking the ALA I feel sub par. Usually a day after finishing 3-day course, feel like a truck has run over me.