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9th Invest in ME International ME Conference, 2014 - Part 1: Autoimmunity and ME
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My experience with DHEA

Discussion in 'General Treatment' started by justy, Mar 6, 2014.

  1. Ema

    Ema Senior Member

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    I took them together at night once and had some bizarre head feelings...and have been afraid to take them together at all since. Just curious if you'd noticed anything. It could have been a one-off.[/quote]

    I have heard it make people sleepy also but i think it's certain oral versions as it converts to a different type of pregnenlone, maybe this was at higher dose too. Can't remember the specifics. Or may have had something to do with progesterone production or something like that? ?[/quote]
    Yeah, oral progesterone converts to allopregnanolone which is extremely sedating in most people. It sedated me for most of the next day as well which is why it didn't work for me at all!

    Hopefully when I'm ready to wean again, I will also be done with the Valium so it won't make a difference. It just doesn't make much sense to me to take a GABA agonist with an antagonist at the same time!
  2. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    I have read that pregnenalone can improve gaba sensitivity too. So who knows. Another thing that is individual to each other??
  3. Ema

    Ema Senior Member

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    Either that or just not tested enough to really know...

    It took 150 mg of pregnenolone to get my levels up into the optimal range. I was also a little worried about taking that much long term. But it must have all been flowing downstream as fast as I took it in....
  4. adreno

    adreno 3% neanderthal

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    Pregnenolone makes my thinking clearer, but it also helps when I can't sleep...cortisol will improve sleep, so it could be that, I don't know. I've taken benzos and other gaba agonists with no problems while on it.
  5. adreno

    adreno 3% neanderthal

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    Yeah I've taken the MLM version... Can't say it is much better, it's supposed to be slow release, I don't feel much difference.

    I've had bad experience with HC and avoid it.
    heapsreal likes this.

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