Hard to write but I thought I would do for the sake of those who consider ARV treatment. Having failed to find a doctor to prescribe them and monitor me, out of desperation (severe ME, mainly neurological symptoms, cognitive impairment) I bought AZT and TEN online. Couldn't afford RAL. After my first attempt, both med stogether, in four days I ended up womiting uncontrollably (plus 10/10 headache) and later having a bad diarrhoea. Got better with the help of my GP in a week's time (still feelig sick but able to eat andtake meds). Decided to take AZT alone. Still made me sick but without throwing up. With every day I took it, I felt worse, till in a week's time I was so ill that had to stop it. In a week repeated it again with the same results, also lasted a week and had to stop for the same reasons. Then, after a while decided to take just one tab AZT per day. Unfortunately, had to stop this, too. This self-treatment gave mne ever increasig general malaise, really strong muscle and joint pains (never had them before), feeling like the area around a pussy zit and only exacerbated by massage or warmth, other my symptoms getting worse, cogitive abilities declining noticeably (now I can't talk or listen more than one pharise at a time, and an attempt to cocentrate on it makes my head spin, and feel really ill; for some reason I still can write but can't read what I've written) and paresthesia getting really bad and constant. Can't really describe how my head feels. Swelled brain feeling, then the strongest burning sensation, touching the head brings all sorts of weird sensations, find it hard to lie because the pressure from the pillow seems overwhelming and I have to turn on the other side, only to have to turn again in a couple of minutes. Sheer agony. Constant spells of dizziness. Don't think it's due to restricted blood flow. I used to take Nimodiphin, IV Cerebrolysin and other prescription drugs used for head injury and stroke patients to improve blood circulation and it didn't do a thing. I don't evenmentionNiacin flash and Ginkgo. The thing is I stopped my unfortunate attempts of taking ARVs (intolerance?) more than a month ago, but am gradually going downhill, with the last days feeling my worst and paresthesia and flashing in front of my eyes getting really really bad. So, I just thought I would warn other desperate people out there that ARV don't bring relief to everybody and persisting in hope that one'll get better eventually actually may do even more damage. I know that if I stopped after #1 attempt, I wouldn't be feeling the way I do. And now I don't even know how to stop this downhill slide. I won't be checking my post, so sorry for any mistakes you find. Also, I may not be able to reply soon, so better don't ask me anything. No, didn't test for XMRV. Mitkovits' statistic made me think that everybody with ME has it.