Hi folks, just wondering if anyone has experienced calf muscle cramps on waking, or chest tightness, or spinal tension whilst on Trazodone. I started 50mg per night two months ago for sleep (also waking in the middle of the night with very low mood). Very positive lift in mood for first 5 days (I remembered what feeling 'normal' was!) then no effect on mood, so I assumed the improved sleep helped me feel better emotionally. The 50mg helped me sleep but the effect began to wear off so I went up to 100mg. Within a week I had chest tightness/ pain. Came off it, did a treadmill ECG and heart was fine. Went back on 50mg. Calf muscle cramping every morning after sleeping, very mild chest tightness over heart area, moderate thoracic spine tightness as if my vertebrae are locked up in that area of the spine, with some mild soreness. GP doesn't seem to be too interested. It feels like he maybe doesn't believe that such a small dose could cause such side effects, particularly since the ECG was clear.