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Murine Leukemia Viruses: Biology and Replication

Discussion in 'XMRV Research and Replication Studies' started by Jemal, Jul 27, 2011.

  1. Jemal

    Jemal Senior Member

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    Not about XMRV specifically, but the family of MLV's.

    http://www.hindawi.com/journals/av/aip/403419/
  2. currer

    currer Senior Member

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    This paper has some nice diagrams at the end. The main text is bichemistry heavy though - a word of warning!

    It closes with a reference to the development of MLVs as gene vectors, an innovation it treats as inevitable.

    Does this seem wise to anyone, until we know whether "wild" mlvs are in the population?

    Gene vectors are modified so that they cannot replicate, but if they meet an unmodified "wild" MLV in a cell they could recombine to become infectious again.
    Not an inviting prospect.
  3. Jemal

    Jemal Senior Member

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    No, it sounds insane.

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