Does anyone know of potential risks from vaccines for the A1298C mutation? If you know my story, I began treating for MTHFR (A1298C mutation) by a practitioner who doesn't understand the whole issue and haven't been the same since. I reached a point where I couldn't tolerate ANY food b/c it led to difficulty breathing and head pressure. I also developed multiple chemical sensitivity. After seeing multiple drs and one making a connection to mast cells/histamine, I think this is causing my problems. However, I just remembered I also got 3 vaccines before taking a trip to Brazil JUST before this mess started for me. I've read one person state that vaccines can cause the mast cells to become overactive, leading to an increase in histamine. I think this could be the cause for my problems. Is anyone aware of this connection? I also want to determine if I have a mast cell disorder or was this just a one-time deal of mast cell problems caused by the vaccines? But it has been 8 months, and I"m not better, in fact much, much worse.