Hi, I'm posting this for a friend with MTHFR. Please tell what steps she should take, what tests/supplements would be helpful in her condition, would an full comprehensive Amy Yasko test help? Any guidance would be appreciated. " I am 66 years old. My mother is getting ready to turn 96. My dad died at age 73 from lung cancer (he smoked for years). At age 16 I became suicidal & depressed because my boyfriend broke up with me. I was a depressed and a rebellious teenager. My parents put me in a mental hospital which began 5 years of going in and out of every mental hospital in the area, sometimes for 1 year at a time. I was in the best private hospitals to a state institution. They tried every treatment on me from no meds, to group therapy, to private therapy, to shock treatments, and then wanted to do a lobotomy which I refused to sign off on! (Thank goodness!) I was finally released from all hospitals and moved out on my own. This was back in the 60s so drugs were everywhere! I got into every drug available. I finally met my future husband, who saved my life by loving me! I got pregnant and we have lived happily ever after. My self confidence grew and everything fell into place. We spent years talking about our pasts and growing together, but I was able to "get well" just by being in a loving relationship. When I was 50 I was diagnosed with Hepatitis C. I have no idea how I got it. I gave up all alcohol and cigarettes. I have never been treated for Hep C. For 16 years I have been taking milk thistle and I watch my liver enzymes. At age 55 I came down w colon cancer, had surgery and chemo for 6 months. They decided to take my gall bladder while they were cutting my colon! 11 years later (present time) I am doing fine. I have not eaten meat in 40 years. In the past 11 years I have gone from vegetarian to vegan to high fat raw to mostly raw and try to stick to 80-10-10. I found Dr Morse about 2 years ago. About a 1 year & a half ago I was told I had both MTHFR genetic defects. I have gone back and forth using supplements and since I don't have any current symptoms that I know of, I don't know what to do. In the past 2 years my toes have become numb. I don't know if this is a result of the chemo from 11 years ago or the MTHFR defect. In the past 5 years I have experienced what I think is venous insufficiency in both legs. If I stand for long periods of time for several days in a row or fly in an airplane, my feet swell and my legs get little red dots (leaking blood vessels?) all over them which can turn into an infection. I just started taking horse chestnut capsules to see if it can build up my veins. So that's my little health history. I feel great, I am always happy, since going raw I have no aches or pains in my body. My weight is good and I live a happy and fulfilling life. I appreciate any insight you have or any guidance you can give me." Oh and if anyone knows a practitioner of methylation in Washington DC, it would be helpful.