Hi. Sorry for my english. For 5 years I suffer from these symptoms: 1. Chronic fatigue 2. Brain fog, derealization 3. Anxiety, depression 4. IBS-D 5. Light, sound sensitivity 6. Afterimages, visual snow 7. Constant ringing in ears, tinnitus 8. High blood pressure 9. Gas, bloating 10. Hair loss 11. Weight loss 12. Feeling my heart beats in my head 13. Panic attacks 14. Lots of dreams at night, restless sleep 15. Stuffy nose My fatigue is mental. It’s hard for me to speak to people, to think, but at the same time I can run and ride my biсycle (but not so easy as before). I don’t know if this condition is chronic fatigue syndrome. I found, many people on this forum have these symptoms. I made a lot of blood work, and the only thing I found was high billirubin (I have Gilberts syndrome), high cholesterol and low vitamin D (11.8). Docs prescribed me antidepressants and tranquilizers, but I had side effects. They say, I need to reduce my anxiety level, to get my symptoms subside. After 3 years of psychotherapy and healthy lifestile I had some progress. Now I have normal blood pressure, no panic attacks, less derealization, my ibs is gone after starting gluten free diet. I tried different supplements: 5htp, GABA, St. Johns wort, B6, valerian root. And after 1-2 day after taking any of these I have one side effect - insomnia and agitation. Even when I washed my nose every day and began to breath easily, after 3 days I have to stop because of terrible insomnia. So, 2 weeks ago I had a complex genetic test for celiac. Celiac genes are negative, but found I have MTHFR 667c homozygous mutation. After that I tested my homocysteine level and it was 22, when the maximum limit is 12. After that, I’v tried Thorne 5-MTHF 0.3 mg (I took 1/3 of 1mg capsule) and after 3 days i’ve got insomnia again. My anxiety got better, but I can’t function because of strong insomnia (hard to fall asleep, restless sleep with lots of vivid dreams). Do you have any thoughts about these supplements, nose breathing, MTHFR and insomnia connection?