"A common mutation at position 1958 within the MTHFD1 gene results in a transition of guanine to adenine (G>A) that may result in a reduction in folate metabolism. In some populations individuals who are homozygote for (1958AA) are reported to have a higher risk for neural tube defects, gastric cancer, schizophrenia and bipolar depression. " http://www.baylorhealth.edu/Researc...ydrogenase(MTHFD1)G1958Amutationanalysis.aspx I can't find a lot of info on this one. I am wondering how much it reduces the ability to methylate folate. Anyone know about this?