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MS symptoms 'eased' by pregnancy

Discussion in 'Other Health News and Research' started by Marco, May 25, 2012.

  1. Marco

    Marco Grrrrrrr!

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    Near Cognac, France
    From BBC Scotland

    Ongoing research looking at why the symptoms of some autoimmune diseases ease during pregnancy :


    http://www.bbc.co.uk/news/uk-scotland-18164859
     
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  2. SilverbladeTE

    SilverbladeTE Senior Member

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    Somewhere near Glasgow, Scotland
    Ah, I knew there were more good reasons to "spawn"! :p
    Well at least I can still think about it :alien:


    One of my all time fave movie lines ;)

     
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  3. Calathea

    Calathea Senior Member

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    I bet they're not including ME amongst the conditions they're researching. Pity. Still, let's hope this is well-conducted research and shows up something useful.
     
  4. TheMoonIsBlue

    TheMoonIsBlue Senior Member

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    I saw a video and article online a while back about a woman who was able to put her MS in remission with hormone therapy. Some special kind of estrogen I think? I guess it mimics pregnancy?

    Some people with FM have said that just BC pills have helped their pain due to hormone flucuatations, but I am super scared to try the pill again.

    The hormone therapy they were using for MS was different than just "the pill" though.
     
  5. Calathea

    Calathea Senior Member

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    I asked around about this a while ago, as the Pill is meant to make your body make it think it's pregnant. The short answer is that the Pill only does this in a fairly crude fashion, and the elements which cause remission in auto-immune diseases are not present in the Pill. Relaxin was one part of it, as I recall.
     
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  6. TheMoonIsBlue

    TheMoonIsBlue Senior Member

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    Thats interesting Calathea. I always have know that hormone fluctuations have triggered a lot of my health problems, from the time I was in my teens. But the pill provided minimal help. My PMS may have been a little less severe but I felt much moodier overall.

    I would be willing to work with someone super smart with hormones to try and create this situation of mimicking pregnancy to see if it helps.

    I took that pill Yasmin, or Yaz, for years, and now there are commericals on all the time for lawsuits against the drug manufacturer!
     
  7. Marco

    Marco Grrrrrrr!

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    Near Cognac, France
    One of the reasons I posted this was that I thought I recalled some anecdotes here that some ME/CFS folks' symptoms improved during pregnancy. I may have been mistaken.

    Its also an under researched area and what information there is is equivocal :


    http://www.prohealth.com/library/showarticle.cfm?libid=13780

    Not enough data I'm afraid to support a clear suspicion of ME/CFS as an autoimmune disease
     
  8. SilverbladeTE

    SilverbladeTE Senior Member

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    Somewhere near Glasgow, Scotland
    PS
    sorry if my levity seemed bad, folks, just well you know me! :sluggish:

    Over the years there's been several items showing affects of pregnancy on autoimmune diseases
    since it drastically alters a woman's hormnal and possibly immune "clock", it would help (or hinder) ME as well?
     
  9. Calathea

    Calathea Senior Member

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    It can go either way with ME, from what I've heard. A substantial number of women improve dramatically when pregnant, but a fair number get worse. Unfortunately, pregnancy isn't just something you can undergo purely as a health treatment - I don't think anyone would want us as surrogates!
     
  10. TheMoonIsBlue

    TheMoonIsBlue Senior Member

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    Not to mention the baby still has to COME OUT some way :p
     
  11. Valentijn

    Valentijn Senior Member

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  12. TheMoonIsBlue

    TheMoonIsBlue Senior Member

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    If their condition returns or worsens after childbirth I hope they have 24/7 help with the baby!

    It would also seem likely that many with ME would have issues with post partum depression given our usually already abnormal reactions to hormone fluctuations that happen just with the menstrual cycle.
     
  13. roxie60

    roxie60 Senior Member

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    The one pregnancy I had was the best I felt ever, had more energy, did something to my hair (would no longer take a perm,not sure relevant). Sadly miscarried week 13. Now no children.
     
  14. Glynis Steele

    Glynis Steele Senior Member

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    Hope it's ok for me to post this here, I wasn't sure whether to start a new thread with this one. It does not mention any particular condition, but I thought it was interesting anyways. T cells mentioned.

    Pregnancy: Why Mother's Immune System Does Not Reject Developing Fetus as Foreign Tissue

    ScienceDaily (June 7, 2012) — Researchers at NYU School of Medicine have made an important discovery that partially answers the long-standing question of why a mother's immune system does not reject a developing fetus as foreign tissue.

    "Our manuscript addresses a fundamental question in the fields of transplantation immunology and reproductive biology, namely, how do the fetus and placenta, which express antigens that are disparate from the mother, avoid being rejected by the maternal immune system during pregnancy?" explained lead investigator Adrian Erlebacher, MD, PhD, associate professor of pathology and a member of the NYU Cancer Institute at NYU Langone Medical Center. "What we found was completely unexpected at every level."
    The researchers discovered that embryo implantation sets off a process that ultimately turns off a key pathway required for the immune system to attack foreign bodies. As a result, immune cells are never recruited to the site of implantation and therefore cannot harm the developing fetus.....

    ......"This is a very exciting finding for us because it gives a satisfying explanation for why the fetus isn't rejected during pregnancy, which is a fundamental question for the medical community with clear implications for human pregnancy," Dr. Erlebacher said. "It also reveals a new modality for controlling T cell trafficking in peripheral tissues that could provide insight into a myriad of other conditions and diseases."

    Follow link for full article:

    http://www.sciencedaily.com/releases/2012/06/120607142244.htm
     
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