That's really interesting, George! Leo Kanner, who coined the term Autism for that condition, said he began to see it in 1938 and published the first paper in 1943. Does anyone know how early vaccinations were made? Mice? There was intense pressure as far back as the turn of the 20th century, to mass vaccination against widespread and dangerous diseases. I've always been a fan of vaccination. All of us who work(ed) in international development were. The risk/benefit ratio seemed a no brainer. It may still be but it may be a more complex issue than we thought. I just don't know anything any more.