Hi there Catherine. Not an expert by any means, but can say what has worked for me. Everybody seems to respond slightly different to supplements, so what works for me probably not going to work exactly for you. Chorella is a chelator, I would have to avoid that in my case. It causes stomach/leg cramping. I never had much luck with D-ribose. B complex helps me. I got it down to where I know kind of which individual b's work, but for most people probably a good b complex is a safe starting point. I would consider adding methylfolate and a b12 per RIch Van K's protocol, and if you tolerate the methylfolate and B12 ok. Consider freddd's protocol. That's what I would do, but you may want to do your homework (and get more feedback) and see what applys to your situation.