I post this for my wife Vanitta. She is a 38 years old thai woman suffering from headaches, sometimes fibromyalgia-like pains, low energy and allergies (hives and sneezing). She is mostly allergic to dust mites but even a mosquito bite can become annoying. Also she has insomnia, a kind of insomnia where she can get a deep sleep for 3 or mostly 4 hours then she gets what she defines as "lucid dreams", a very light sleep or even no sleep at all. Sometimes she experiences numbness in the fingers. A hair analysis showed - low molybdenum: .001 with reference range .003-.008 - copper on the low normal: 1.0 with reference .9-3.9 - normal zinc: 17 with reference 10-21 - high zinc/copper ratio: 17 with reference 4-12 Then she tested for ceruloplasmin and it's quite low at 12.40 (reference 20-60). Some of her symptoms are compatible with low molybdenum or even a form of Wilson desease. But urinary copper 24 hours (NOT challenged with penicillamine) is very low at <5.0 µg and as I understand, should theoretically exclude Wilson desease. Hemoglobin is slighty low at 10.5 as well as slightly low hematocrit at 34, also compatible with low copper. AST and ALT are in the range: 22 and 15 U/L. She has CBS mutations C699T and A360A +/- which can lead to increased ammonia and sulfites and which should benefit from molybdenum. All in all, looks like she might improve her symptoms through molybdenum supplementation, but we are concerned about her low copper. Molybdenum is supposed to antagonize copper, which is already low in her. But then I read from the Linus Pauling Institute web site at http://lpi.oregonstate.edu/mic/minerals/molybdenum that "An early study reported that molybdenum intakes of 500 mcg/day and 1,500 mcg/day from sorghum increased urinary copper excretion (2). However, the results of a more recent, well-controlled study indicated that very high dietary molybdenum intakes (up to 1,500 mcg/day) did not adversely affect copper nutritional status in eight, healthy young men (9)." So we are quite confused whether supplementing with molybdenum. Any experience?