Proteins of the XMRV retrovirus implicated in chronic fatigue syndrome and prostate cancer are homologous to human proteins relevant to both diseases. http://precedings.nature.com/documents/4669/version/1 Anyone remember this paper? If the HGRV present in people with CFS is similar to the sequence used in this paper, could the reduction in CFS symptoms in the recent Rituximab trial be due to reduction of infected B cells? Or could it be that the b cells population that produces autoantibodies to the proteins mentioned in this paper are depleted and thereby reduce symptoms? Better said, could this be a retrovirally induced autoimmune disease?