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Mixing metroprolol, levothyroxine and melatonin... Good or bad idea?

Discussion in 'General Treatment' started by Kenjie, Apr 25, 2017.

  1. Kenjie

    Kenjie Senior Member

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    I take all these.. Although melatonin only last 2 nights to get my sleep back on track after 3 nighys trouble sleeping due to hot flashes and constant peeing.

    But today I'm a bit anxious or on the edge of it and feeling slightly unsteady again when walking.

    Been on levo for 5 yes. Metroprolol 2-3 weeks with increase on dosage a week or so ago.

    Just wondered if this mix can mess with hormones...
     
  2. deleder2k

    deleder2k Senior Member

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    I couldn't find any interactions. If you experience side effects from the medicines you take I think you should talk to your doctor.
     
  3. Snowdrop

    Snowdrop Rebel without a biscuit

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    Wouldn't your Dr or pharmacist/chemist be best able to advise since they are ones prescribing/filling your Rx?
     
  4. Alvin2

    Alvin2 If humans were rational...

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    I will bet money levothyroxine and melatonin are not going to interfere with each other because both are found in normal people and there are no problems. That said 1mg of melatonin is what a normal brain produces so more then that is possible to interact though unlikely but more important has little extra effect in most cases and is just a waste of money.
    The metoprolol (beta blocker) i don't know, it should be fine interaction wise because again normal people who have normal thyroid and melatonin function can take it without interference, but its possible the drug is not agreeing with you rather then an interaction with the first two.

    If you have an arrhythmia or have had a heart attack or other coronary issues which is why your on the beta blocker then thats probably the direction to look into
     
  5. Kenjie

    Kenjie Senior Member

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    I've been put on the beta blocker to improve my symptoms but this is without an official diagnosis. Doctors haven't been able to tell me anything for certain. New doctor says he gave me the beta blocker for my symptoms including lowering my BPM.
     
  6. Eian Mcneely

    Eian Mcneely

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    Hi Kenjie, good to know they are adding beta blocks kindly keep us updated......
     
  7. Kenjie

    Kenjie Senior Member

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    I'd prefer to have early menopause than pots... That I could deal with as menopause isn't for life lol...

    I'm 35...
     
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  8. Alvin2

    Alvin2 If humans were rational...

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    Some people don't do well taking supplemental melatonin, it plays with the body clock and when taken at the wrong time (the wrong phase) people sometimes get symptoms from nightmares to insomnia to possibly hot flashes. Not to say the melatonin is harmful but it can take some tinkering to get it right and some people find it just doesn't work out for them.

    The beta blocker is a another kettle of fish, what symptoms are they giving to you for, if its for for ME/CFS then i don't think it will help and may cause problems, though other members who have tried it may have different opinions.

    Making two changes at once makes it harder to pin down the cause of problems since it could be either one. I still think its unlikely to be a mixing them problem, but perhaps worth stopping the melatonin and see what happens. If symptoms still there stop the beta blocker (advise doctor on this one).
     
  9. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    Beta blockers will ruin your sleep if the dose is high enough because they reduce your body's production of melatonin.

    https://www.ncbi.nlm.nih.gov/pubmed/10335905
    Carvedilol will not reduce production of melatonin but it might make you too drowsy during the day since it has to be taken twice a day in order to be effective. I've taken atenolol, metoprolol and carvedilol so I can also tell you this from experience.

    I tried to find information about the interaction between melatonin and the thyroid gland. It was mixed. I think this answer from WebMD, not written by someone who is an MD, might be helpful:
    http://answers.webmd.com/answers/50...plements-work-on-patients-with-hypothyroidism

    I think the best thing to do would be to ask an endocrinologist their opinion about taking melatonin.
     
    merylg likes this.
  10. Research 1st

    Research 1st Severe ME, POTS & MCAS.

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    Before doing anything to your brain, I would check your Melatonin levels via tests.

    I checked mine and they are normal, and I can barely sleep.
     
  11. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    Here's information specific to the effect of metoprolol on melatonin:

    https://www.ncbi.nlm.nih.gov/pubmed/3291558
     
    Kenjie likes this.

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