@pattismith @BeautifulDay Linda Avey's 23andMe data is posted her: https://www.snpedia.com/index.php/User:Lilly_Mendel And here is a direct link to her 23andMe v4 data as an example. https://s3.amazonaws.com/snpedia/User/Lilly_Mendel/genome_Lilly_Mendel_v4.txt.gz I believe here husbands file is also available somewhere..... I don't know how to decode the raw data file to see the 4 mutations of interest to get another data point without paying the $40 to Enlis. Maybe you are interested to take a look? As an aside - Linda was one of founders 23andMe and is now working on ME with precise.ly. One of her friends has ME. Precisely are part of one of the NIH centers working with Deva and Lucinda Bateman. In 1H2018 they will be updating their app to support HELIX genetic data specifically to look at ME aspects. Could be worth reaching out to her on things we'd like to see from the Precisely/Helix combination.