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Mitochondrial Cocktail

Discussion in 'General Treatment' started by cman89, Jun 15, 2015.

  1. cman89

    cman89 Senior Member

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    If I could theoretically take a cocktail of supplements to regenerate/heal/boost Mitochondria function and genesis, with (theoretical) cost not being a factor, what would you include in this (likely massive) supplement regimen? (and I mean anything and everything) Ideally, I would like to not have listed supplements that are "reported" to increase Mitochondria, but where medical lit has good reports for effectiveness. If all issues (DNA, Function, Genesis, Cell wall integrity, and acidosis) Could potentially be covered by this theoretical cocktail, that would be awesome.
     
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  2. ahmo

    ahmo Senior Member

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  3. Wayne

    Wayne Senior Member

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    Hi @cman89

    Thanks for posting this--I've been sort of wondering the same thing. I saw a post recently by a PR member who claimed to have found a very effective mitochondrial supplement, but I somehow lost track of it. o_O I hope that poster will show up on this thread and re-post her testimonial.
     
  4. dannybex

    dannybex Senior Member

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    Catseye was bedridden at one point, and the last I heard was doing really well. Here's one of her many posts on mitochondria (which includes a lot of supplements -- where she talks about Coenzyme A -- she did find a supplement by that name that included all of the ingredients she lists here):

    http://forums.phoenixrising.me/inde...ve-a-big-picture-theory.386/page-3#post-10898

    One of her main points is fixing leaky gut first. She does insist on a certain diet. I think that diets will be different for everyone, but she talks about the one that helped her the best.

    @Wayne -- I think that supplement is the "Biotec Extra Energy Enzymes" that Catseye talks about. But they seem to be either out of business, or just making the pet versions now. There is a bitter melon SOD enzyme product put out by Seeking Health though…

    :)
     
  5. *GG*

    *GG* Senior Member

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    Oh, guess this would make more sense than CoQ10, I'm upping my dosage of that :)

    GG
     
  6. pogoman

    pogoman Senior Member

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    in no particular order

    coq10
    B2 riboflavin
    L-carnitine
    Choline
    branch chained amino acids
    creatine
    D-ribose
    L-citrulline
    caffeine
     
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  7. cman89

    cman89 Senior Member

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    No b12 in that mix? esp. Adenosylcobalamin?
     
  8. cman89

    cman89 Senior Member

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    This is good info folks, lets keep it going...
     
  9. Wayne

    Wayne Senior Member

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    How about DCA (DiChloroAcetate)? It's a low-cost prescription drug that's been used for decades to treat mitochondrial disorders. More recently it's been used to successfully treat cancer. Interestingly, last I checked, it was being sold on Amazon as a veterinary product for animals with cancer.
     
  10. pogoman

    pogoman Senior Member

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    i consider B12 more to be with methylation than the krebs cycle altho both are related.
    plus some are sensitive to methyl products but if one has mthfr or similar then by all means it should be included along with folate.
     
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  11. cman89

    cman89 Senior Member

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    Do you have an idea how it works?
     
  12. leokitten

    leokitten Senior Member

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    I didn't see it mentioned here (maybe I missed it) but in addition to supplements mentioned you should also take PQQ, it promotes mitochondrial biogenesis.
     
    SOC likes this.
  13. SOC

    SOC Senior Member

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    Have you read anything about appropriate dosage for PQQ?
     
  14. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    Even though these things are meant to increase energy, what about ways to reduce pem after activity?
    I wonder if it would be best to use a pem treatment on an as needs basis or preemptive when we definitely know we are going to get hit. I wonder if using something all the time can reduce it's effects.

    So what could we use to treat pem? I know @SOC increase q10 dose. Inflammation is said to increase, I have thought of maybe an anti inflammatory and an antihistamine to help reduce inflammation. Maybe increase normal dose of carnitine and antioxidants when we have pem. To help replace energy use a combo of creating, ribose, pyruvate, bcaa, glutamine and maybe use larger doses than one would use if they took them regularly.

    I'm still looking into different substances that could be used for a pem recovery as well as substances to help mitochondria function well. I do use b12 injections when in a crash and they help some.

    So any more thoughts on not just supporting mitochondria but also a pem recovery strategy?

    Cheers
     
  15. cman89

    cman89 Senior Member

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    I have heard of pqq. Very interested to try.
     
  16. cman89

    cman89 Senior Member

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    Actually, yes I do. Anything that could reduce the pH burden of the blood and tissues overall could potentially help with PEM. It can protect the cells from the oxidative damage which is said to be seen in CFS PEM. One easily accessible substance is Baking Soda, or Sodium Bicarbonate. Drinking it mixed in H2O can help some folks, but it can also create gas and other gut issues.
     
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  17. leokitten

    leokitten Senior Member

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    20 mg/day from what I read in research studies is more than sufficient, any more than that gets very expensive. I think if cost is an issue you would be fine with even 10 mg/day.
     
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  18. knackers323

    knackers323 Senior Member

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    Apart from the one member mentioned. Are many people helped much by mitochondrial treatment?

    Is it worth the test?
     
    sillysocks84 likes this.
  19. sillysocks84

    sillysocks84 Senior Member

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    AMPK is another
     

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