Actually I know someone who says their MS medicine is making them worse. Of course there are other meds, but neuros tend to have a favorite treatment and be really stubborn about it. Some days I want to send the majority of neurologists back to school. Though that's not the only kind of specialist I've had insist I should take a certain medicine that didn't necessarily have any good science to back it up. Maybe we should just send make sure that the training people take in order to maintain licensure, covers what makes good evidence, how to read a research paper, treating patients as individuals, etc.