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Miriam Tucker: Immune-Modulating Agents Eyed for 'Chronic Fatigue Syndrome'

Discussion in 'Latest ME/CFS Research' started by Cheshire, Nov 11, 2016.

  1. Cheshire

    Cheshire Senior Member

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    http://www.medscape.com/viewarticle/871787?src=soc_tw_share
     
  2. daisybell

    daisybell Senior Member

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    Miriam Tucker has been busy since the conference! It's great to see three good articles appear in Medscape in quick succession - hopefully health professionals reading those will be struck by the evidence for biological disease.
     
    mango, GodGenghis, BurnA and 12 others like this.
  3. Webdog

    Webdog Up to 91% remain undiagnosed

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    California
  4. Sidereal

    Sidereal Senior Member

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    Miriam Tucker's article are always excellent.

     
    mango, Mel9, L'engle and 16 others like this.
  5. Never Give Up

    Never Give Up Collecting improvements, until there's a cure.

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    Mel9, L'engle, Solstice and 5 others like this.
  6. Strawberry

    Strawberry Senior Member

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    Haven't some people here been injured by immune modulators? I want to say Ginger Girl (intentionally not tagging her) might have, and it seems others I have read were too. But my brain is pretty worthless at times.
     
    L'engle and Luther Blissett like this.
  7. Navid

    Navid Senior Member

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    This sounds like very big, helpful news. Do we know if Ron Davis ' team is involved in this at all. Makes it seem like they already have some drugs in mind and it all fits in with the Metabalon findings of Naviuex, Gordon, Davis....etc.
     
    WendyM, L'engle and Luther Blissett like this.
  8. Battery Muncher

    Battery Muncher Senior Member

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    Sorry, haven't been paying attention. Could someone link all three of Tucker's articles? Thanks
     
    L'engle likes this.
  9. caledonia

    caledonia

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    https://en.wikipedia.org/wiki/Pyruvate_dehydrogenase_complex

    Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that convert pyruvate into acetyl-CoA.

    This conversion is inhibited by mercury, arsenic and antimony. These metals also inhibit other conversions farther along in the Kreb's cycle.

    Mercury and lead also inhibit methionine synthase, aka screw up the methylation cycle. Mercury also screws up many other enzymes and pathways in the body (CBS/transsulfuration) is another example.
     
    L'engle likes this.
  10. A.B.

    A.B. Senior Member

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    The committment by Fluge and Mella to this illness is much appreciated. Especially that they are also looking at genetics, metabolomics, blood vessels, and other things besides B cell depletion (which may very well turn out to help only a subset).
     
    mango, RL_sparky, Mel9 and 4 others like this.

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