I've been prescribed midrodine for NMH and started off at 2.5mg plus sodium tablets, 3 times a day. That dose had no effect on my BP or symptoms after ten days so yesterday I was told to increase the midrodine to 5mg, 3 times a day. It didn't do much for my BP but it did seem to improve my symptoms slightly but noticeably, particularly by the evening. I was looking forward to the effect building, but this morning I had a migraine (not unusual for me) with loss of visual field and an arc of sparkling lights (once a decade) and the on-call GP has advised me to drop my dose back down until I can speak to the prescribing doctor at the hospital. Anybody have problems ramping up? Or no problems ramping up? How fast did you up your dose?