I started taking midodrine yesterday. I'm after input from people who have ME and POTS and take midodrine. When you take it you're not meant to lie down for 4 hours. Now for me that's quite a long time to not lie down/put my feet up. Does taking midodrine at the right dose take away the need to lie down? Do you take it less often for this reason? Eg my doctor prescribed it 3x a day but maybe I should take once a day and have a more upright 4 hours? If I just keep my head elevated do you think this is enough? I've just got a blood pressure monitor. If my blood pressure isn't high do you think it is ok to lie down? Is this the only reason for the advice? I also take bisoprolol and ivabradine. This is in addition.