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Methylfolate dosage?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Bdeep86, Sep 30, 2013.

  1. Bdeep86

    Bdeep86 Senior Member

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    Was wonder what dose of methylfolate do people generally settle on? For either Rich or Freddd? I have a lot of Bh4 issues as well so i'm wondering if I need higher doses.
     
  2. Bdeep86

    Bdeep86 Senior Member

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    Have you noticed improvements with those doses? How much B12 are you on?
     
  3. Star-Anise

    Star-Anise Senior Member

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    Bdeep86
    Yep, I have been using the 1500mcg daily of methylB12 that I split into 3 doses - no other forms of B12 right now. I have been slowly tapering this dose up over past 3 mos, along with my methylfolate which I am at 250mcg per day right now.
    I have noticed vast improvements in my energy, stamina, and cognition over past 3 months from introducing methylfolate & methylB12. As I read might be the case though I was unable to increase my doses dramatically until I got my mercury filling removed, which appeared to be leaking (yuck). I am now facing the challenge of chelation in my future...
     
    helen1 likes this.
  4. caledonia

    caledonia

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    Cincinnati, OH, USA
    I was just looking at Rich's protocol so this is fresh in my mind: 200mcg methylfolate. I get a response from that amount.
     
  5. helen1

    helen1 Senior Member

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    I'm on 700 mcg slowly ramped up from 100 mcg. I might be seeing an improvement, not sure.
     
  6. Critterina

    Critterina Senior Member

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    I see people on these forums who max out at a few hundred micrograms, others who take 10-30 milligrams. It really depends on how you respond.

    I am trying to substitute some folinic acid for the MTHF, since I don't have the MTHFR C677T, and since MTHF is so expensive. I take 5 mg of MTHF and one or two 800 mcg of folinic. I'm also taking TMG because of BHMT 08 mutation, so I figure I've got enough methyl groups hanging around to methylate the folinic acid. I have always had perfect skin even as a teenager and now I'm post menopausal, but my face and scalp broke out for several months when I was on 1 mg of MTHF. It's better but not great now, which is why I'm trying two of the folinic this week.
     

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