New era for ME/CFS research as top cytokine study attracts media headlines
The immune systems of patients who have recently developed ME/CFS look markedly different from those who have been ill for much longer, according to a major new study from Drs. Ian Lipkin and Mady Hornig at Columbia University. This shift in immune function hadn’t been seen before.
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Methylation test results

Discussion in 'Diagnostic Guidelines and Laboratory Testing' started by erist, Sep 6, 2012.

  1. erist

    erist

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    Twin Cities
    Wondering if anyone wants to give their input on these Methylation test results from ELN? Blue is low, black is normal, red is high. You will see that most things are "out of range", but not by that much. Wondering what the body/mind sensitivity is to some of these levels and if these numbers mean I'm a good candidate for a methylation trial and/or if they are often "abnormal" in healthy people as well. Likely I will give it a trial no matter what to see if I notice an improvement, but in put is always nice

    Glutathione (oxidised) .45 (.16-.5)
    Glutathione (reduced) 3.0 (3.8-5.5)

    SAM 207 (221-256)
    SAH 42.6 (38-49)

    (SAM+SAH = ~250)

    Folic Acid Derivates
    5-CH3-THF 6.3 (8.4-72.6)
    10-Formyl-THF 2.0 (1.5-8.2)
    5-formyl-THF 1.3 (1.2-11.7)
    THF .44 (.6-6.8)
    Folic Acid 8.0 (8.9-24.6)
    Folinic Acid (WB) 7.2 (9.0-35.5)
    Folic Acid, active (RBC) 331 (400-1500)

    Adenosine 21.8 (16.8-21.4)
     
  2. August59

    August59 Daughters High School Graduation

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    Upstate SC, USA
  3. richvank

    richvank Senior Member

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    HI, erist.

    Here are some comments on your results:

    You have glutathione depletion and some oxidative stress.

    You have a partial block of your methylation cycle at methionine synthase.

    You may be low in methionine (which feeds the methylation cycle).

    You may have one or more upregulating SNPs in your CBS enzyme.

    Your folate status is generally low.

    Your adenosine is slightly high, but will probably normalize when the partial block is lifted.

    The Simplified Methylation Protocol should help you.

    Best regards,

    Rich
     
  4. erist

    erist

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    Twin Cities
    Thanks Rich! My chronic fatigue and lyme doctor speaks highly of you. Listening to your long presentations on it now.
     

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