Posted this over in Tests and diagnostics but figured I'd post them here too. Just got these sad results from health diagnostics and research institute and wonder what to do about them. Any advice most welcome. oxidized glutathione 0.54 0.16 - 0.50 reduced glutathione 3.2 3.8 - 5.5 s-adenosylmethionine (SAMe) 220 221- 256 s-adenosylhomocysteine (SAH) 53.6 38 - 49 5 CH3 tetrahydrafolate 10.7 8.4 - 72 10 formyl tetrahydrafolate 5.9 1.5 - 8.2 5 formyl tetrahydrafolate 2.0 1.2 - 11.7 tetrahydrafolate 0.49 0.5 - 6.8 folic acid 9.3 8.9 - 24 folinic acid (whole blood) 8.0 9 - 35 active folate (RBC) 327 400 - 1500 adenosine 22.9 16.8 - 21.4 I don't understand how I have any folic acid as I haven't eaten any enriched wheat products in over a year and no wheat at all for 4 months or more. Very few grains too except for the occasional brown rice or quinoa. Does it hang around for months? I eat a lot of folinic rich veggies plus I was taking folinic acid for several months before the test, so don't understand that low score. Not sure about the significance of the different folates (except folic acid and folinic acid). I have read Rich's explanation, but am looking for advice specific to my results. I've been on a combo SMP/freddd for about a year, including methylfolate titrated up to 400 mcg for 6 months. Also adB12 1500 mcg, mB12 1000 mcg. Plus all the cofactors. Looks like I need a lot more methylfolate. Just started supplementing with SAMe. Any other ideas? Anyone have success improving their glutathione for a sustained period of time? Anyone know the significance of a high adenosine level? Thanks in advance.