Thanks for this info, Marlene. I don't take any methyl folate or folinic for now. But I will keep in this in mind when I start taking it. I've been slowly increasing my B12 (over the past 3 years) from a crumb to about 1000 mcg. That's been a LONG road. Like you, I also take HB12 and MB12, but have not tolerated the AdB12. I take glutamine every night before bed (2-3 grams) with a probiotic. It really helps my gut. I haven't tried the molybdenum yet. I bought it because Yasko recommends it for CBS, but I have only the minor CBSA360A snp, and seem to be doing okay without molybdenum for now. I'm going to get my blood drawn for the HDRI test this week, and am eager to see what the results will be like. It took them a longgggg time to send me the kit. ONE QUESTION for you: Which B Complex do you take? Thanks again, for your input on this.